دواعي استعمال توسيبكت-ن شراب 100 مل
معلومات من نشرات دوائية ومراجع موثقة، مع مصدر كل معلومة. السعر الحالي: 10ج.م.
دواعي الاستعمال
- Productive cough, chest congestion, acute and chronic bronchitis, bronchial asthma symptoms and cough with common cold/flu.
الآثار الجانبية
- Common: drowsiness, nausea, dry mouth, headache, stomach discomfort; rare: palpitations, nervousness, allergic reactions.حسب الشركة المنتجة
موانع الاستعمال
- Hypersensitivity to any ingredient; narrow-angle glaucoma; severe cardiovascular disorders; children under 6 years without medical supervision.حسب الشركة المنتجة
تحذيرات واحتياطات
- Theophylline has a narrow therapeutic range; many conditions (extremes of age, heart failure, fever, liver disease) and drugs reduce its clearance; serious adverse effects become more likely above serum concentrations of 20 mcg/mL.معلومة عامة عن المادة الفعالة
- Diphenhydramine: do not use with other diphenhydramine-containing products; ask a doctor first with glaucoma, breathing problems or an enlarged prostate.معلومة عامة عن المادة الفعالة
- Guaifenesin: ask a doctor first with persistent or chronic cough (smoking, asthma, chronic bronchitis, emphysema) or cough with excessive phlegm.معلومة عامة عن المادة الفعالة
التداخلات الدوائية
- Theophylline metabolism inhibitors (e.g. cimetidine, erythromycin)Raise theophylline levels; toxicity risk.
- Metabolism inducers (e.g. carbamazepine, rifampin)Lower theophylline levels; stopping them raises levels.
- Other xanthines, macrolides (erythromycin), sedatives/CNS depressants, beta-blockers, digitalis glycosidesListed as potential interactions by the retailer page.
الحمل والرضاعة
- Theophylline is excreted into breast milk at about the maternal serum concentration and may cause irritability or mild toxicity in the infant.معلومة عامة عن المادة الفعالة
كيف يعمل الدواء
- ديفينهيدرامين: Competitive H1-receptor antagonism; central antitussive effects.
- جوايفينيسين: May irritate gastric vagal receptors recruiting parasympathetic reflexes that increase less-viscous respiratory secretions.مذيب بلغم
- ثيوفيلين: Relaxes airway smooth muscle (bronchodilation) and suppresses airway responsiveness to stimuli; bronchodilation is thought to be mediated by inhibition of phosphodiesterase isozymes PDE III and, to a lesser extent, PDE IV (US label; mechanisms not known with certainty).ميثيل زانثين (مثبط فوسفوديستراز)
المصادر
- السعر: قوائم أسعار الأدوية المنشورة في مصر.