دواعي استعمال الستوب 20مجم 14 كبسول
معلومات من نشرات دوائية ومراجع موثقة، مع مصدر كل معلومة. السعر الحالي: 42.4ج.م.
دواعي الاستعمال
- Treatment of active duodenal ulcer and of active benign gastric ulcer.الفئة: AdultsDailyMed (U.S. National Library of Medicine)
- Helicobacter pylori eradication (triple or dual therapy) to reduce the risk of duodenal ulcer recurrence.الفئة: AdultsDailyMed (U.S. National Library of Medicine)
- Treatment of symptomatic GERD, treatment of erosive esophagitis due to acid-mediated GERD and maintenance of its healing.الفئة: Adults and pediatric patientsDailyMed (U.S. National Library of Medicine)
- Pathological hypersecretory conditions (e.g. Zollinger-Ellison syndrome).الفئة: AdultsDailyMed (U.S. National Library of Medicine)
موانع الاستعمال
- Known hypersensitivity (including anaphylaxis) to omeprazole, any substituted benzimidazole or any component of the formulation.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Patients receiving rilpivirine-containing products.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
تحذيرات واحتياطات
- Symptomatic response does not preclude gastric malignancy; consider follow-up and diagnostic testing.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Acute tubulointerstitial nephritis, Clostridioides difficile-associated diarrhea, bone fracture with long-term high-dose use, severe cutaneous adverse reactions, cutaneous and systemic lupus erythematosus have been reported.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Long-term use may cause vitamin B12 deficiency, hypomagnesemia and mineral metabolism disturbances, and fundic gland polyps.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
التداخلات الدوائية
- ClopidogrelOmeprazole reduces the pharmacological activity of clopidogrel; avoid concomitant use.DailyMed (U.S. National Library of Medicine)
- RilpivirineContraindicated: PPIs reduce rilpivirine exposure.DailyMed (U.S. National Library of Medicine)
- St. John's Wort or rifampinMay substantially decrease omeprazole concentrations; avoid concomitant use.DailyMed (U.S. National Library of Medicine)
- MethotrexateConcomitant use (mainly high-dose methotrexate) may elevate and prolong methotrexate levels; consider temporary PPI withdrawal.DailyMed (U.S. National Library of Medicine)
الحمل والرضاعة
- No adequate and well-controlled studies in pregnant women; epidemiologic data fail to demonstrate an increased risk of major congenital malformations with first-trimester omeprazole use.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Limited data suggest omeprazole may be present in human milk; no data on effects on the breastfed infant or on milk production.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
كيف يعمل الدواء
- أوميبرازول: Suppresses gastric acid secretion by inhibiting the H+/K+ ATPase (proton pump) of the gastric parietal cell.
المصادر
- السعر: قوائم أسعار الأدوية المنشورة في مصر.
- DailyMed (U.S. National Library of Medicine)
- PubChem (NCBI)