دواعي استعمال التراجريزوفلفين 125مجم 20 قرص

Ultragriseofulvin: griseofulvin 125 mg oral tablets, pack of 20 (2 strips); systemic antifungal by Kahira Pharmaceuticals.

• Treatment of dermatophyte infections of the skin, hair and nails (ringworm: tinea corporis, pedis, cruris, barbae, capitis, unguium) caused by Trichophyton, Microsporum or Epidermophyton speciesDailyMed (U.S. National Library of Medicine)

• Hypersensitivity reactions such as skin rashes and urticaria; rarely angioneurotic edema, erythema multiforme-like eruptions; also oral thrush, nausea, vomiting, epigastric distress, diarrhea, headache, fatigue, dizziness, insomnia, mental confusion; rarely proteinuria and leukopenia (discontinue if granulocytopenia occurs).نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Contraindicated in pregnancy (griseofulvin may cause fetal harm; rare reports of conjoined twins).نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Contraindicated in patients with porphyria or hepatocellular failure, and in patients with a history of hypersensitivity to griseofulvin.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Severe skin reactions (e.g. Stevens-Johnson syndrome, toxic epidermal necrolysis) and erythema multiforme have been reported; discontinue if they occur.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Hepatotoxicity (elevated AST/ALT, bilirubin, jaundice) has been reported; monitor and discontinue as appropriate.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Possible cross-sensitivity with penicillins (griseofulvin is a Penicillium derivative); photosensitivity reactions may occur and lupus erythematosus or lupus-like syndromes may be aggravated.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Warfarin-type anticoagulantsGriseofulvin decreases the activity of warfarin-type anticoagulants; dosage adjustment of the anticoagulant may be needed during and after griseofulvin therapy.DailyMed (U.S. National Library of Medicine)
• BarbituratesBarbiturates usually depress griseofulvin activity; concomitant use may require a dosage adjustment of the antifungal.DailyMed (U.S. National Library of Medicine)
• Oral contraceptivesGriseofulvin may reduce the efficacy of oral contraceptives and increase breakthrough bleeding.DailyMed (U.S. National Library of Medicine)
• AlcoholPotentiation of the effect of alcohol (e.g. tachycardia and flush) has been reported.DailyMed (U.S. National Library of Medicine)

• Contraindicated in women who are pregnant; griseofulvin may cause fetal harm.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• In prolonged therapy, periodically monitor organ-system function, including renal, hepatic and haematopoietic function.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)