دواعي استعمال يوناسين 375مجم 12 قرص

معلومات من نشرات دوائية ومراجع موثقة، مع مصدر كل معلومة. السعر الحالي: 60ج.م.

دواعي الاستعمال

Infections caused by susceptible organisms, including upper and lower respiratory tract infections (sinusitis, otitis media, tonsillitis, bacterial pneumonia, bronchitis), urinary tract infections and pyelonephritis, skin and soft-tissue infections, and gonococcal infections.Pfizer Medical Information (labeling.pfizer.com)

الآثار الجانبية

Common: candidiasis, headache, diarrhoea, nausea, vomiting, abdominal pain, rash and pruritus.نشرة دولية لنفس التركيبة · Pfizer Medical Information (labeling.pfizer.com)

موانع الاستعمال

Hypersensitivity to any penicillin or to any component of the product.نشرة دولية لنفس التركيبة · Pfizer Medical Information (labeling.pfizer.com)

تحذيرات واحتياطات

Serious, occasionally fatal hypersensitivity (anaphylactic) reactions and severe cutaneous adverse reactions (SJS, TEN, DRESS, AGEP) have been reported; stop treatment if they occur.نشرة دولية لنفس التركيبة · Pfizer Medical Information (labeling.pfizer.com)
Superinfection with non-susceptible organisms, including Candida, may occur; Clostridioides difficile-associated diarrhoea has been reported.نشرة دولية لنفس التركيبة · Pfizer Medical Information (labeling.pfizer.com)
Drug-induced liver injury, including cholestatic hepatitis and jaundice, has been reported; monitor hepatic function in patients with hepatic impairment.نشرة دولية لنفس التركيبة · Pfizer Medical Information (labeling.pfizer.com)
Avoid in infectious mononucleosis because of the high frequency of rash with ampicillin.نشرة دولية لنفس التركيبة · Pfizer Medical Information (labeling.pfizer.com)
Tablets contain lactose; patients with hereditary galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption should not take them.نشرة دولية لنفس التركيبة · Pfizer Medical Information (labeling.pfizer.com)

التداخلات الدوائية

AllopurinolIncreased incidence of rash with concomitant allopurinol.Pfizer Medical Information (labeling.pfizer.com)
Oral anticoagulantsPenicillins may alter platelet aggregation and coagulation tests; effects may be additive with anticoagulants.Pfizer Medical Information (labeling.pfizer.com)
Bacteriostatic antibiotics (chloramphenicol, erythromycin, sulfonamides, tetracyclines)May interfere with the bactericidal effect of penicillins; avoid concurrent use.Pfizer Medical Information (labeling.pfizer.com)
Oral contraceptives (oestrogen-containing)Reduced contraceptive effectiveness has been reported with ampicillin; an additional or alternative method is advisable.Pfizer Medical Information (labeling.pfizer.com)
MethotrexatePenicillins reduce methotrexate clearance, increasing toxicity; monitor closely.Pfizer Medical Information (labeling.pfizer.com)
ProbenecidProbenecid reduces renal tubular secretion of ampicillin and sulbactam, raising and prolonging serum concentrations.Pfizer Medical Information (labeling.pfizer.com)

الحمل والرضاعة

Safety in human pregnancy not established; use only if the expected benefit outweighs the possible risk.نشرة دولية لنفس التركيبة · Pfizer Medical Information (labeling.pfizer.com)
Ampicillin and sulbactam pass into breast milk in low amounts; use in breastfeeding is not recommended / requires caution because of possible effects on the infant (sensitisation, diarrhoea, candidiasis).نشرة دولية لنفس التركيبة · Pfizer Medical Information (labeling.pfizer.com)

المتابعة أثناء العلاج

Ampicillin may cause false-positive urine glucose results with copper-reduction (Benedict/Fehling/Clinitest) methods; use enzymatic glucose oxidase tests.نشرة دولية لنفس التركيبة · Pfizer Medical Information (labeling.pfizer.com)

المصادر