دواعي استعمال يوناسين 375مجم فيال

معلومات من نشرات دوائية ومراجع موثقة، مع مصدر كل معلومة. السعر الحالي: 15.75ج.م.

دواعي الاستعمال

Skin and skin structure infections caused by susceptible beta-lactamase-producing strains of Staphylococcus aureus, E. coli, Klebsiella spp., Proteus mirabilis, Bacteroides fragilis, Enterobacter spp. and Acinetobacter calcoaceticus.DailyMed (U.S. National Library of Medicine)
Intra-abdominal infections caused by susceptible beta-lactamase-producing strains of E. coli, Klebsiella spp., Bacteroides spp. and Enterobacter spp.DailyMed (U.S. National Library of Medicine)
Gynecological infections caused by susceptible beta-lactamase-producing strains of E. coli and Bacteroides spp.DailyMed (U.S. National Library of Medicine)

الآثار الجانبية

Most common adverse reactions: injection-site pain (16% IM, 3% IV), thrombophlebitis (3%), diarrhea (3%) and rash (<2%).معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)

موانع الاستعمال

History of serious hypersensitivity reactions (e.g. anaphylaxis or Stevens-Johnson syndrome) to ampicillin, sulbactam or other beta-lactam antibacterials (penicillins, cephalosporins).معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)
History of cholestatic jaundice or hepatic dysfunction associated with UNASYN.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)

تحذيرات واحتياطات

Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported; discontinue and treat if an allergic reaction occurs.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)
Hepatotoxicity, including hepatitis and cholestatic jaundice, has been reported; monitor hepatic function at regular intervals in patients with hepatic impairment.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)
Severe cutaneous adverse reactions (SJS, TEN, DRESS, AGEP) have been reported; discontinue if they occur.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)
Clostridioides difficile-associated diarrhea has been reported and may range from mild diarrhea to fatal colitis.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)
A high percentage of patients with mononucleosis receiving ampicillin develop a skin rash; ampicillin-class antibacterials should not be given to these patients.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)

التداخلات الدوائية

ProbenecidProbenecid decreases renal tubular secretion of ampicillin and sulbactam, resulting in increased and prolonged blood concentrations.DailyMed (U.S. National Library of Medicine)
AllopurinolConcurrent allopurinol and ampicillin increases the incidence of rash compared with ampicillin alone.DailyMed (U.S. National Library of Medicine)

الحمل والرضاعة

Use during pregnancy only if clearly needed.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)
Low concentrations of ampicillin and sulbactam are excreted in milk; use with caution in nursing women.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)

المصادر