دواعي استعمال يونيكابتوبريل 50مجم 20 اقراص

Captopril 50 mg tablets, pack of 20 (Unipharma, Egypt); ACE inhibitor.

• Hypertensionالفئة: AdultsDailyMed (U.S. National Library of Medicine)

• Rash (often maculopapular, with pruritus) in about 4-7 of 100 patients; proteinuria in about 1 of 100; neutropenia/agranulocytosis reported.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to captopril or any other ACE inhibitor (e.g. history of angioedema during ACE inhibitor therapy).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Do not co-administer with aliskiren in patients with diabetes.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Do not administer with a neprilysin inhibitor (e.g. sacubitril) or within 36 hours of switching to or from sacubitril/valsartan.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Boxed warning - fetal toxicity: when pregnancy is detected discontinue captopril as soon as possible; drugs acting on the renin-angiotensin system can cause injury and death to the developing fetus.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Neutropenia/agranulocytosis has occurred, particularly in patients with renal impairment and collagen vascular disease; proteinuria (about 1 in 100 patients) has been reported.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Contraindicated in effect by boxed warning: discontinue as soon as pregnancy is detected because of fetal toxicity.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Captopril is excreted in human milk at about 1% of maternal blood levels; decide whether to discontinue nursing or the drug.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)