دواعي استعمال يوريكنترول اس ار 4 مجم 12 كبسولة

Tolterodine L-tartrate 4 mg prolonged-release capsules (Pharco).

• Symptomatic treatment of urge incontinence and/or increased urinary frequency and urgency as may occur in overactive bladder syndrome.electronic Medicines Compendium (eMC)

• Mild to moderate antimuscarinic effects; dry mouth most common (23.4% vs 7.7% placebo); also dyspepsia and dry eyes.نشرة دولية لنفس التركيبة · electronic Medicines Compendium (eMC)

• Urinary retention; uncontrolled narrow-angle glaucoma; myasthenia gravis; hypersensitivity to tolterodine or excipients; severe ulcerative colitis; toxic megacolon.نشرة دولية لنفس التركيبة · electronic Medicines Compendium (eMC)

• Use with caution in significant bladder outlet obstruction, gastrointestinal obstructive disorders (e.g. pyloric stenosis), renal impairment, hepatic disease, autonomic neuropathy, hiatus hernia and risk of decreased GI motility.نشرة دولية لنفس التركيبة · electronic Medicines Compendium (eMC)
• May cause accommodation disturbances and affect reaction time; ability to drive or use machines may be impaired.نشرة دولية لنفس التركيبة · electronic Medicines Compendium (eMC)

• Potent CYP3A4 inhibitors (erythromycin, clarithromycin, ketoconazole, itraconazole, antiproteases)Concomitant systemic use not recommended: raised tolterodine levels in CYP2D6 poor metabolisers with risk of overdose.electronic Medicines Compendium (eMC)
• Other antimuscarinic drugs / muscarinic agonistsAntimuscarinics may increase effects and side effects; muscarinic cholinergic agonists may reduce tolterodine's effect.electronic Medicines Compendium (eMC)

• No adequate data in pregnant women; animal studies showed reproductive toxicity; not recommended during pregnancy.نشرة دولية لنفس التركيبة · electronic Medicines Compendium (eMC)
• No data on excretion into human milk; avoid during lactation.نشرة دولية لنفس التركيبة · electronic Medicines Compendium (eMC)