دواعي استعمال اورسوكول 500مجم 30 اقراص

Ursodeoxycholic acid (ursodiol) 500 mg film-coated tablet, a bile acid.

• Dissolution of radiolucent, non-calcified gallbladder stones <20 mm in patients at increased surgical risk or who refuse surgery.الفئة: AdultsDailyMed (U.S. National Library of Medicine)
• Prevention of gallstone formation in obese patients undergoing rapid weight loss.الفئة: AdultsDailyMed (U.S. National Library of Medicine)

• Calcified cholesterol, radiopaque or radiolucent bile pigment stones; compelling reasons for cholecystectomy (unremitting acute cholecystitis, cholangitis, biliary obstruction, gallstone pancreatitis, biliary-GI fistula); allergy to bile acids.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Bile acid sequestrants (cholestyramine, colestipol)May reduce ursodiol absorption.DailyMed (U.S. National Library of Medicine)
• Aluminium-based antacidsAdsorb bile acids and may reduce ursodiol effect.DailyMed (U.S. National Library of Medicine)
• Estrogens, oral contraceptives, clofibrateIncrease hepatic cholesterol secretion and may counteract ursodiol.DailyMed (U.S. National Library of Medicine)

• Animal reproduction studies showed no harm to the fetus at 20-100x (rat) and 5x (rabbit) human doses; some reduced fertility at 100-200x in rats.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Unknown whether excreted in human milk; use with caution in nursing mothers.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Measure AST and ALT at initiation and thereafter as clinically indicated.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• حمض الأورسوديوكسيكوليك: حمض صفراوي محب للماء يقلل تشبع الصفراء بالكوليسترول وقد يحمي الخلايا الكبدية.حمض صفراوي