دواعي استعمال Zovirax 500 mg 5 i.v. inf. vial

Zovirax 500 mg IV infusion, 5 vials, by GlaxoSmithKline, Egypt: aciclovir (as sodium) for intravenous infusion (antiviral).

• Initial and recurrent mucosal and cutaneous herpes simplex (HSV-1, HSV-2) in immunocompromised patientsDailyMed (U.S. National Library of Medicine)
• Severe initial episodes of herpes genitalis in immunocompetent patientsDailyMed (U.S. National Library of Medicine)

• Hypersensitivity to acyclovir or valacyclovir.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Precipitation of acyclovir crystals in renal tubules can occur if solubility is exceeded or with bolus injection, causing acute renal failure.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Not teratogenic in mouse, rabbit or rat studies; no adequate well-controlled studies in pregnant women.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• After oral dosing, breast-milk concentrations were 0.6-4.1 times plasma levels (infant exposure up to 0.3 mg/kg/day); use with caution.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• أسيكلوفير: Guanine nucleoside analogue phosphorylated by viral thymidine kinase; the triphosphate inhibits viral DNA polymerase and terminates DNA chain elongation.