سعر الفافيم 600مجم 20 كبسولة 2024

Egyptian food-supplement capsules combining thioctic (alpha-lipoic) acid 600 mg with ginkgo biloba extract, vitamins B6 and B12, folic acid and bacopa extract (20 capsules), by Copad Pharma; promoted for diabetic neuropathy and as an antioxidant.

• Reported adverse effects include allergic skin reactions (rash, hives, itching), abdominal pain, nausea, vomiting, diarrhea and dose-dependent vertigo; malodorous urine reported at 1,200 mg/day.General active-ingredient information · Linus Pauling Institute Micronutrient Information Center (Oregon State University)
• Ginkgo leaf extract is generally well tolerated; the most common side effects are dizziness, gastrointestinal symptoms and headache.General active-ingredient information · NIH National Center for Complementary and Integrative Health (NCCIH)

• Lipoic acid may lower blood glucose; people with diabetes using insulin or oral antidiabetic agents should monitor blood glucose closely.General active-ingredient information · Linus Pauling Institute Micronutrient Information Center (Oregon State University)
• Accidental ingestion by young children can be dangerous: a case of intoxication in a 20-month-old child after 4 x 600 mg tablets has been reported. Keep out of reach of children.General active-ingredient information · Linus Pauling Institute Micronutrient Information Center (Oregon State University)

• Insulin / oral antidiabetic agentsAdditive glucose-lowering effect is possible; monitor blood glucose.Linus Pauling Institute Micronutrient Information Center (Oregon State University)
• BiotinLipoic acid and biotin have similar structures and may compete for transport; high lipoic acid intake could theoretically affect biotin status.Linus Pauling Institute Micronutrient Information Center (Oregon State University)
• Anticoagulants (e.g. warfarin)Ginkgo may increase the risk of bleeding in people taking anticoagulants.NIH National Center for Complementary and Integrative Health (NCCIH)
• CycloserineVitamin B6 supplements might worsen seizures and nerve damage caused by cycloserine.NIH Office of Dietary Supplements
• MethotrexateFolate supplements could interfere with methotrexate when it is used to treat cancer.NIH Office of Dietary Supplements
• Antiepileptics (phenytoin, carbamazepine, valproate)These drugs can lower folate levels, and folate supplements could lower blood levels of these medicines.NIH Office of Dietary Supplements

• Safety in pregnancy is not well established; use only under strict medical supervision (limited observational data at 600 mg/day without reported adverse effects).General active-ingredient information · Linus Pauling Institute Micronutrient Information Center (Oregon State University)
• Ginkgo may be unsafe during pregnancy; it might cause early labor or extra bleeding during delivery if used near that time.General active-ingredient information · NIH National Center for Complementary and Integrative Health (NCCIH)
• Safety during breastfeeding has not been established; use is discouraged.General active-ingredient information · Linus Pauling Institute Micronutrient Information Center (Oregon State University)
• Little is known about whether ginkgo is safe during breastfeeding.General active-ingredient information · NIH National Center for Complementary and Integrative Health (NCCIH)

• Alpha-lipoic acid (thioctic acid): Cofactor of mitochondrial dehydrogenase complexes; free lipoic acid and dihydrolipoic acid act as antioxidants (Linus Pauling Institute).