سعر اميروبيم 500مجم فيال وريد 2024

Meropenem 500 mg per vial sterile powder in a single vial for intravenous injection or infusion after reconstitution (Ameropem, Pharco B); a broad-spectrum carbapenem antibiotic for serious bacterial infections.

• Complicated skin and skin structure infections due to susceptible bacteriaPopulation: Adults and pediatric patients 3 months of age and olderDailyMed (U.S. National Library of Medicine)
• Complicated intra-abdominal infections (complicated appendicitis and peritonitis)Population: Adults and pediatric patientsDailyMed (U.S. National Library of Medicine)
• Bacterial meningitis caused by H. influenzae, N. meningitidis and penicillin-susceptible S. pneumoniaePopulation: Pediatric patients 3 months of age and olderDailyMed (U.S. National Library of Medicine)

• Most common adverse reactions (>2%): headache, nausea, constipation, diarrhoea, anaemia, vomiting and rash.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to any component of the product or to other carbapenems, or anaphylactic reactions to beta-lactams.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Serious and occasionally fatal hypersensitivity (anaphylactic) reactions; ask about previous reactions to penicillins, cephalosporins and other beta-lactams before starting.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Severe cutaneous adverse reactions (SJS, TEN, DRESS, erythema multiforme, AGEP); discontinue if they occur.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Rhabdomyolysis: discontinue if signs occur (muscle pain or weakness, dark urine, elevated CPK).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Valproic acid / divalproex sodiumCo-administration reduces valproic acid concentrations below the therapeutic range, increasing the risk of breakthrough seizures; concomitant use is generally not recommended.DailyMed (U.S. National Library of Medicine)
• ProbenecidProbenecid competes for renal tubular secretion and increases meropenem plasma concentrations; co-administration is not recommended.DailyMed (U.S. National Library of Medicine)

• Insufficient human data to establish a drug-associated risk of major birth defects or miscarriage; no fetal toxicity or malformations in rats and monkeys at doses up to about 2.3-2.4 times the maximum recommended human dose.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Meropenem is excreted in human milk; weigh the benefits of breastfeeding against the mother's clinical need and potential adverse effects on the infant.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Meropenem: Bactericidal: inhibits bacterial cell-wall synthesis by penetrating the cell wall of most Gram-positive and Gram-negative bacteria and binding penicillin-binding proteins (PBPs); not active against MRSA or MRSE (US label).