سعر اموكسيسيللين ستادا 1000مجم 12 قرص 2022

Amoxicillin 1000 mg film-coated tablets, pack of 12 (2 strips); aminopenicillin antibiotic.

• Most common adverse reactions (>1%) in clinical trials of capsules, tablets or oral suspension: diarrhea, rash, vomiting and nausea.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Postmarketing reports: mucocutaneous candidiasis; DIES, black hairy tongue and hemorrhagic/pseudomembranous colitis; hypersensitivity reactions including anaphylaxis, angioedema and serum sickness-like reactions; rashes, erythema multiforme, SJS, TEN, DRESS, AGEP; raised AST/ALT and hepatic dysfunction including cholestatic jaundice; crystalluria; anemia, thrombocytopenia, eosinophilia, leukopenia, agranulocytosis; CNS effects (hyperactivity, agitation, insomnia, confusion, convulsions, aseptic meningitis); tooth discoloration, mostly in children.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• History of a serious hypersensitivity reaction (e.g., anaphylaxis or Stevens-Johnson syndrome) to amoxicillin or to other beta-lactam antibacterial drugs (e.g., penicillins or cephalosporins).General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported with penicillins including amoxicillin; inquire about previous hypersensitivity to penicillins, cephalosporins or other allergens and discontinue if a reaction occurs.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Severe cutaneous adverse reactions (SJS, TEN, DRESS, AGEP) may occur; monitor patients who develop a rash closely and discontinue if lesions progress.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Drug-induced enterocolitis syndrome (DIES), mostly in patients 18 years or younger, presenting as protracted vomiting 1-4 hours after ingestion; discontinue amoxicillin and institute appropriate therapy.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Clostridioides difficile-associated diarrhea, ranging from mild diarrhea to fatal colitis, may occur even over 2 months after antibacterial use; evaluate patients who develop diarrhea.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• A high percentage of patients with mononucleosis who receive amoxicillin develop an erythematous skin rash; amoxicillin should not be given to patients with mononucleosis.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• ProbenecidDecreases renal tubular secretion of amoxicillin, which may result in increased and prolonged blood levels of amoxicillin.DailyMed (U.S. National Library of Medicine)
• Oral anticoagulantsAbnormal prolongation of prothrombin time (increased INR) has been reported; monitor appropriately and adjust the anticoagulant dose if necessary.DailyMed (U.S. National Library of Medicine)
• AllopurinolConcurrent use increases the incidence of rashes compared with amoxicillin alone.DailyMed (U.S. National Library of Medicine)
• Combined oral contraceptivesAmoxicillin may affect intestinal flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral estrogen/progesterone contraceptives.DailyMed (U.S. National Library of Medicine)
• Chloramphenicol, macrolides, sulfonamides and tetracyclinesMay interfere with the bactericidal effects of penicillin (demonstrated in vitro; clinical significance not well documented).DailyMed (U.S. National Library of Medicine)

• Reproduction studies in mice and rats at doses up to 2000 mg/kg showed no evidence of fetal harm; there are no adequate and well-controlled studies in pregnant women; use during pregnancy only if clearly needed.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Penicillins are excreted in human milk; amoxicillin use by nursing mothers may lead to sensitization of infants - exercise caution.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Monitor renal function in elderly patients and prothrombin time/INR in patients on oral anticoagulants; watch for rash progression and diarrhea. For urine glucose testing use enzymatic glucose oxidase methods (copper-reduction tests may give false-positive results).General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Amoxicillin: Bactericidal against susceptible bacteria during active multiplication through inhibition of cell-wall biosynthesis; susceptible to degradation by beta-lactamases (US labels).