سعر انجيتكت 60 مجم 20 قرص 2022

Diltiazem hydrochloride 60 mg film-coated tablets (non-dihydropyridine calcium channel blocker), pack of 20 tablets (2 strips), marketed in Egypt by Marcyrl.

• Management of chronic stable anginaPopulation: AdultsDailyMed (U.S. National Library of Medicine)
• Management of angina due to coronary artery spasmPopulation: AdultsDailyMed (U.S. National Library of Medicine)

• In trials: edema (2.4%), headache (2.1%), nausea (1.9%), dizziness (1.5%), rash (1.3%), asthenia (1.2%).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Sick sinus syndrome or second-/third-degree AV block except with a functioning ventricular pacemaker.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Hypotension (systolic < 90 mmHg); hypersensitivity to diltiazem; acute myocardial infarction with pulmonary congestion.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Prolongs AV-node refractory periods; may cause bradycardia and AV block, especially with beta-blockers or digitalis.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Use with caution in impaired ventricular function/congestive heart failure; symptomatic hypotension; acute hepatic injury reported.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• CYP3A4 substrates, inhibitors and inducers; P-gp substratesDiltiazem is a CYP3A4 substrate and inhibitor: exposure of co-administered drugs (e.g., benzodiazepines, statins, cyclosporine) or of diltiazem may change.DailyMed (U.S. National Library of Medicine)
• Beta-blockers, digitalisAdditive effects on AV conduction and heart rate; digoxin levels may increase.DailyMed (U.S. National Library of Medicine)

• Use during pregnancy only if the potential benefit justifies the potential risk to the fetus (animal studies at 5-10 times the human dose showed embryo-fetal lethality; no well-controlled studies in pregnant women).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Excreted in human milk (concentrations may approximate serum levels); if use is essential, an alternative method of infant feeding should be used.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Diltiazem: Inhibits calcium influx through slow channels in cardiac and vascular smooth muscle, dilating coronary and peripheral arteries and slowing AV-nodal conduction.