سعر افيشيست 375مجم 20 كبسولة 2022

Carbocisteine 375 mg hard capsules, pack of 20 (Avichest, listed under Sanofi in Egypt); mucolytic.

• Adjunctive therapy of respiratory tract disorders characterised by excessive, viscous mucus, including chronic obstructive airways disease.Population: Adults including the elderlyelectronic medicines compendium (emc), UK

• Frequency not known: allergic skin eruptions, anaphylactic reactions and fixed drug eruption; gastrointestinal bleeding; epigastric discomfort, nausea, vomiting and diarrhoea; skin rashes; isolated cases of bullous dermatitis such as Stevens-Johnson syndrome and erythema multiforme.International label, same formulation · electronic medicines compendium (emc), UK

• Hypersensitivity to carbocisteine or to any of the excipients.International label, same formulation · electronic medicines compendium (emc), UK
• Active peptic ulceration.International label, same formulation · electronic medicines compendium (emc), UK

• Caution in the elderly, in patients with a history of gastroduodenal ulcers, or taking concomitant medicines known to cause gastrointestinal bleeding; discontinue if gastrointestinal bleeding occurs.International label, same formulation · electronic medicines compendium (emc), UK
• The UK capsules contain lactose (22 mg per capsule): not for patients with galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Excipients of the Egyptian product were not verified.International label, same formulation · electronic medicines compendium (emc), UK

• Medicines known to cause gastrointestinal bleedingThe SmPC lists no interactions (section 4.5 "None stated") but advises caution with concomitant medicines known to cause gastrointestinal bleeding.electronic medicines compendium (emc), UK

• Use in lactation: effects not known.International label, same formulation · electronic medicines compendium (emc), UK

• Carbocisteine: Mucoregulator acting on the gel phase of mucus, probably by breaking disulfide bridges of glycoproteins, which facilitates expectoration; in animal models it normalises the composition of secreted mucus glycoprotein and reduces goblet-cell hyperplasia.