سعر ازكلير 20% كريم 30 جم 2022

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• Topical treatment of acne vulgarisPopulation: Adults and adolescents 12 years and olderelectronic medicines compendium (eMC)
• Topical treatment of mild-to-moderate inflammatory acne vulgarisPopulation: Patients 12 years and olderDailyMed (U.S. National Library of Medicine)

• Very common: application-site burning, pruritus and erythema. Common: application-site exfoliation, pain, dryness, discolouration, irritation. Uncommon: seborrhoea, acne, skin depigmentation, application-site paraesthesia/dermatitis/discomfort/oedema. Rare: cheilitis, application-site vesicles/eczema/warmth/ulcer, hypersensitivity, worsening of asthma. Not known: urticaria, rash, angioedema, contact dermatitis, eye or face swelling.International label, same formulation · electronic medicines compendium (eMC)

• Hypersensitivity to azelaic acid or any excipient.International label, same formulation · electronic medicines compendium (eMC)

• For external use only; avoid contact with eyes, mouth and other mucous membranes (rinse with plenty of water if contact occurs).International label, same formulation · electronic medicines compendium (eMC)
• Worsening of asthma has been reported rarely.International label, same formulation · electronic medicines compendium (eMC)
• The UK product contains benzoic acid (local irritation), propylene glycol and cetostearyl alcohol (local skin reactions); Egyptian excipients not verified.International label, same formulation · electronic medicines compendium (eMC)

• Other medicines (no specific agent)No interaction studies have been performed.electronic medicines compendium (eMC)

• No adequate studies of topical azelaic acid in pregnant women; animal studies suggest potential effects at doses 3-32 times the maximum human dose; use with caution in pregnancy.International label, same formulation · electronic medicines compendium (eMC)
• Embryotoxic effects seen in animals only at high oral doses; use during pregnancy only if clearly needed.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Infants must not come into contact with treated skin or breast; about 0.01% of the dose is estimated to reach the infant via milk; use with caution.International label, same formulation · electronic medicines compendium (eMC)

• Azelaic acid: Antimicrobial action and a direct influence on follicular hyperkeratosis are assumed to underlie its efficacy in acne; reduces Propionibacterium acnes colonisation and inhibits keratinocyte proliferation (Skinoren UK SmPC 5.1).