سعر ازوبت 1% قطرة 5 مل 2022

Azopt: brinzolamide 1% eye drops (ophthalmic suspension), 5 ml bottle; topical carbonic anhydrase inhibitor for raised intraocular pressure. Company: Novartis (Novartis Scientific Office).

• Elevated intraocular pressure in ocular hypertension or open-angle glaucomaPopulation: AdultsDailyMed (U.S. National Library of Medicine)

• Most frequent (5-10%): blurred vision and bitter, sour or unusual taste. 1-5%: blepharitis, dermatitis, dry eye, foreign body sensation, headache, hyperemia, ocular discharge, discomfort, keratitis, pain, pruritus and rhinitis. Postmarketing: Stevens-Johnson syndrome and toxic epidermal necrolysis.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to any component of the product.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Brinzolamide is a sulfonamide and is absorbed systemically; sulfonamide-type reactions (including Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, blood dyscrasias) may occur, rarely fatal. Discontinue if serious reactions or hypersensitivity occur.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Increased risk of corneal edema in patients with low corneal endothelial cell counts; use with caution.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Not studied in acute angle-closure glaucoma, which requires additional therapeutic interventions.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Oral carbonic anhydrase inhibitorsPotential additive systemic effects of carbonic anhydrase inhibition; concomitant use is not recommended.DailyMed (U.S. National Library of Medicine)
• High-dose salicylatesAcid-base alterations have occurred rarely with oral carbonic anhydrase inhibitors and high-dose salicylate therapy; consider this potential interaction.DailyMed (U.S. National Library of Medicine)

• No adequate and well-controlled studies in pregnant women. Oral brinzolamide caused fetal toxicity in rats at 375 times the recommended human ophthalmic dose; no fetal toxicity in rabbits.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• No data on presence in human milk, effects on the breastfed infant or milk production; detected in the milk of lactating rats. Weigh benefits of breastfeeding against the mother's clinical need.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Brinzolamide: Inhibits carbonic anhydrase II in the ciliary processes, decreasing aqueous humor secretion and lowering intraocular pressure.