سعر بندافولين 50 مجم محلول للحقن العضلي/الوريدي أو التسريب 2026

Calcium folinate solution for i.m./i.v. injection or infusion, Egyptian Bendafolin 50 mg presentation (Wasserburger/Pharmakon).

• Calcium folinate rescue: to diminish toxicity and counteract folic acid antagonists such as methotrexate in cytotoxic therapy and overdose (adults and children)Population: Adults and childrenUK eMC / MHRA SmPC
• In combination with 5-fluorouracil in cytotoxic therapyPopulation: AdultsUK eMC / MHRA SmPC

• Immune system: rarely allergic reactions including anaphylactoid reactions and urticaria have been reported with calcium folinate (UK SmPC).International label, same formulation · UK eMC / MHRA SmPC

• Hypersensitivity to calcium folinate or any excipient.International label, same formulation · UK eMC / MHRA SmPC
• Pernicious anaemia or other anaemias due to vitamin B12 deficiency.International label, same formulation · UK eMC / MHRA SmPC

• Must be given by intramuscular or intravenous injection only; must not be administered intrathecally. Deaths have been reported after intrathecal use following intrathecal methotrexate overdose.International label, same formulation · UK eMC / MHRA SmPC
• Use with methotrexate or 5-fluorouracil only under specialist cytotoxic protocols; rescue dosing depends on the methotrexate regimen.International label, same formulation · UK eMC / MHRA SmPC

• No adequate well-controlled studies in pregnant women; no indications that calcium folinate alone induces harmful effects in pregnancy. When used with methotrexate or 5-FU, follow those agents’ pregnancy guidance (methotrexate is contraindicated in pregnancy).International label, same formulation · UK eMC / MHRA SmPC
• It is not known whether calcium folinate is excreted in human milk; decision on breast-feeding should consider the benefit to mother and risk to infant, especially when co-administered with methotrexate or 5-FU.International label, same formulation · UK eMC / MHRA SmPC

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