سعر فولينوبيوجين 300 مجم/30 مل فيال 2022

Calcium folinate (leucovorin calcium) solution in a single vial of 300 mg/30 ml (10 mg/ml), listed in Egypt under Arabcomed-Egypt / Biocapital Pharma.

• Leucovorin rescue after high-dose methotrexate therapy in osteosarcoma.Population: As labelled (US)DailyMed (U.S. National Library of Medicine)
• To diminish toxicity and counteract the effects of impaired methotrexate elimination and of inadvertent overdosage of folic acid antagonists.Population: As labelled (US)DailyMed (U.S. National Library of Medicine)
• Megaloblastic anaemias due to folic acid deficiency when oral therapy is not feasible.Population: As labelled (US)DailyMed (U.S. National Library of Medicine)

• Allergic sensitisation including anaphylactoid reactions, urticaria and anaphylactic shock has been reported.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Improper therapy for pernicious anaemia and other megaloblastic anaemias secondary to vitamin B12 deficiency: a haematologic remission may occur while neurologic manifestations progress.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Leucovorin may be harmful or fatal if given intrathecally; do not administer intrathecally.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Because of its calcium content, no more than 160 mg of leucovorin should be injected intravenously per minute.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Leucovorin enhances the toxicity of 5-fluorouracil; the combination requires supervision by a physician experienced in antimetabolite chemotherapy, with particular care in elderly or debilitated patients.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Phenobarbital, phenytoin, primidoneFolic acid in large amounts may counteract the antiepileptic effect and increase seizure frequency in susceptible paediatric patients.DailyMed (U.S. National Library of Medicine)
• 5-FluorouracilLeucovorin may enhance the toxicity of 5-fluorouracil.DailyMed (U.S. National Library of Medicine)
• Intrathecal methotrexateHigh doses of leucovorin may reduce the efficacy of intrathecally administered methotrexate.DailyMed (U.S. National Library of Medicine)

• Adequate animal reproduction studies have not been conducted; it is not known whether leucovorin causes fetal harm. Give to a pregnant woman only if clearly needed.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• It is not known whether leucovorin is excreted in human milk; use caution in nursing mothers.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

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