سعر بونابكس Bonapex‏ 10مجم 30 قرص 2026

Alendronate 10 mg oral tablets (bisphosphonate) by Multi-Apex.

• Most common (>=3%): abdominal pain, acid regurgitation, constipation, diarrhoea, dyspepsia, musculoskeletal pain, nausea.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Oesophageal abnormalities delaying emptying (stricture, achalasia); inability to stand or sit upright for 30 minutes; hypocalcaemia; hypersensitivity.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Upper GI irritation (oesophagitis, ulcers); correct hypocalcaemia before use; severe bone/joint/muscle pain; osteonecrosis of the jaw; atypical femoral fractures; not recommended in severe renal impairment.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Calcium supplements, antacids, oral medicines with multivalent cationsInterfere with absorption; wait at least 30 minutes after alendronate.DailyMed (U.S. National Library of Medicine)
• Aspirin / NSAIDsIncreased upper GI adverse events; use with caution.DailyMed (U.S. National Library of Medicine)

• Insufficient human data; discontinue when pregnancy is recognised; adverse effects in animal studies.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Unknown whether alendronate is present in human milk; weigh benefits of breastfeeding against maternal need.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Alendronic acid (as alendronate sodium): Binds bone hydroxyapatite and inhibits osteoclast-mediated bone resorption.