سعر بونيناسال 200 وحدة دولية/جرعة بخاخ أنف 2022

Calcitonin 200 IU/dose nasal spray (Mina Pharm).

• Postmenopausal osteoporosis in women >5 years postmenopause when alternatives unsuitable. Fracture-reduction efficacy not demonstrated.Population: Postmenopausal women >5 years postmenopauseDailyMed

• Common (≥3%): rhinitis, epistaxis/nasal symptoms, back pain, arthralgia, headache.International label, same formulation · DailyMed

• Hypersensitivity to calcitonin salmon or excipients.International label, same formulation · DailyMed

• Anaphylaxis risk; correct hypocalcaemia first; nasal ulceration — examine nose periodically; meta-analysis suggests increased malignancy risk — reassess continued need; antibodies may blunt response.International label, same formulation · DailyMed

• LithiumMay lower plasma lithium via increased urinary clearance; adjust lithium if needed.DailyMed

• Not indicated for reproductive-potential females; insufficient human pregnancy data.International label, same formulation · DailyMed
• No human milk data; calcitonin inhibits lactation in rats.International label, same formulation · DailyMed

• Calcitonin salmon: Acts primarily on bone; decreases the rate of bone resorption, associated with fewer osteoclasts and reduced resorptive activity (calcitonin receptors are present on osteoclasts and osteoblasts) (US label).