سعر كالميبام Calmepam‏ 1.5مجم 30 قرص 2026

Calmepam 1.5 mg 30 tablets: bromazepam 1.5 mg tablets marketed in Egypt by GlaxoSmithKline.

• Most frequent: drowsiness, ataxia and dizziness, mainly at the start of treatment.International label, same formulation · Health Canada Drug Product Database

• Hypersensitivity to benzodiazepines; myasthenia gravis; severe hepatic impairment; severe respiratory insufficiency; sleep apnoea syndrome; narrow-angle glaucoma.International label, same formulation · Health Canada Drug Product Database

• Risk of abuse, misuse, addiction, dependence and severe withdrawal reactions; avoid abrupt discontinuation.International label, same formulation · Health Canada Drug Product Database
• Concomitant use with opioids may cause profound sedation, respiratory depression, coma and death.International label, same formulation · Health Canada Drug Product Database
• Impairs driving and operating machinery; falls and fractures risk, especially in the elderly; anterograde amnesia and paradoxical reactions may occur.International label, same formulation · Health Canada Drug Product Database

• OpioidsAdditive CNS depression: profound sedation, respiratory depression, coma, death.Health Canada Drug Product Database
• Alcohol and other CNS depressantsEnhanced sedation and cardio-respiratory depression; avoid alcohol.Health Canada Drug Product Database
• Fluvoxamine, cimetidine (possibly propranolol)Increase bromazepam exposure (fluvoxamine ~2.4-fold AUC; cimetidine reduces clearance by ~50%).Health Canada Drug Product Database

• Should not be used during pregnancy; use in late pregnancy/labour only for strict indication (neonatal hypotonia, hypothermia, respiratory depression, withdrawal possible).International label, same formulation · Health Canada Drug Product Database
• Probably excreted in breast milk; should not be given to nursing mothers.International label, same formulation · Health Canada Drug Product Database

• Bromazepam: Binds the GABA-A benzodiazepine site, facilitating GABA-mediated chloride channel opening and neuronal hyperpolarization (anxiolytic/sedative/muscle-relaxant class effects). Source: Health Canada Apotex BROMAZEPAM Product Monograph 2022-02-14 / class pharmacology.