سعر سيرازيت 75 مكجم 28 قرصاً 2024

Cerazette (Organon > MSD scientific office, Egypt): desogestrel 75 microgram film-coated tablets; pack of 28.

• Oral contraception (progestogen-only pill); primary mechanism inhibition of ovulation with additional cervical mucus thickening (Cerazette SmPC).Population: Women of childbearing potential seeking contraceptionMHRA / eMC — Cerazette SmPC

• Most common: bleeding irregularity (up to ~50%); also acne, mood changes, breast pain, nausea, weight increase; common headache, libido decreased, menstruation irregular/amenorrhoea (Cerazette SmPC).International label, same product · MHRA / eMC — Cerazette SmPC

• Active venous thromboembolic disorder; presence or history of severe hepatic disease until liver function normalizes; known or suspected sex-steroid sensitive malignancies; undiagnosed vaginal bleeding; hypersensitivity to desogestrel or excipients (Cerazette SmPC).International label, same product · MHRA / eMC — Cerazette SmPC

• Discuss breast-cancer risk, VTE history, diabetes monitoring early in use, hypertension, ectopic pregnancy in differential of amenorrhoea/abdominal pain, chloasma, mood changes/depression, reduced efficacy with enzyme inducers or GI upset, lactose intolerance (Cerazette SmPC).International label, same product · MHRA / eMC — Cerazette SmPC

• Hepatic enzyme inducers (e.g. rifampicin, carbamazepine, phenytoin, St John's wort, efavirenz)MajorMay reduce contraceptive efficacy; use barrier during and for 28 days after short-term inducer therapy; consider alternative contraception for long-term inducers (Cerazette SmPC).MHRA / eMC — Cerazette SmPC

• Not indicated during pregnancy; stop if pregnancy occurs. Epidemiological data for COCs/desogestrel-containing COCs do not indicate increased birth-defect risk from inadvertent early exposure (Cerazette SmPC).International label, same product · MHRA / eMC — Cerazette SmPC
• Does not appear to influence milk production/quality in clinical data; small amounts of etonogestrel in milk; may be used during breastfeeding with observation of infant growth/development; infrequent reports of decreased milk production (Cerazette SmPC).International label, same product · MHRA / eMC — Cerazette SmPC

• Desogestrel: Primary contraceptive effect by inhibition of ovulation; also increases cervical mucus viscosity (Cerazette SmPC).