سعر اكسلوتون 0.5مجم 28 قرص 2022

Lynestrenol 0.5 mg progestogen-only oral contraceptive tablets, 28 tablets per pack.

• Contraception (progestogen-only pill), particularly suitable during breastfeeding and for women who cannot or do not wish to use oestrogens.Population: Women of reproductive ageCollege ter Beoordeling van Geneesmiddelen (CBG-MEB) - Geneesmiddeleninformatiebank

• Common: fluid retention, depressed or altered mood, decreased libido, headache, migraine, nausea, abdominal pain, acne, breast pain/tenderness/discharge, irregular bleeding, amenorrhoea, weight gain. Uncommon: vomiting, diarrhoea, contact-lens intolerance, persistent ovarian follicles, vaginal dryness/discharge. Rare: hypersensitivity, urticaria, weight loss.International label, same product · College ter Beoordeling van Geneesmiddelen (CBG-MEB) - Geneesmiddeleninformatiebank

• Active venous thromboembolic disorder; present or past severe hepatic disease while liver function values have not normalised; known or suspected sex-steroid-sensitive malignancies; undiagnosed vaginal bleeding; hypersensitivity to the active substance or excipients.International label, same product · College ter Beoordeling van Geneesmiddelen (CBG-MEB) - Geneesmiddeleninformatiebank

• Weigh benefits and risks in women with risk factors; a possible small increase in breast cancer diagnosis similar to combined pills cannot be excluded; refer women with liver disease; stop if active venous thromboembolism develops and consider stopping during prolonged immobilisation.International label, same product · College ter Beoordeling van Geneesmiddelen (CBG-MEB) - Geneesmiddeleninformatiebank
• Irregular or frequent vaginal bleeding may occur; reliability may be reduced by missed tablets, gastrointestinal disturbance or interacting enzyme-inducing medicines.International label, same product · College ter Beoordeling van Geneesmiddelen (CBG-MEB) - Geneesmiddeleninformatiebank

• Hepatic enzyme inducers (phenytoin, phenobarbital, primidone, carbamazepine, rifampicin; suspected for oxcarbazepine, topiramate, rifabutin, felbamate, ritonavir, nelfinavir, griseofulvin)May increase clearance of sex hormones, causing breakthrough bleeding and/or contraceptive failure.College ter Beoordeling van Geneesmiddelen (CBG-MEB) - Geneesmiddeleninformatiebank

• Not indicated during pregnancy; stop immediately if pregnancy occurs. Very high progestogen doses masculinised female fetuses in animals; epidemiological data with oral contraceptives used before or inadvertently in early pregnancy have not shown increased malformation risk, but this is not specifically known for Exluton.International label, same product · College ter Beoordeling van Geneesmiddelen (CBG-MEB) - Geneesmiddeleninformatiebank
• Does not adversely affect milk production or quality; about 0.14% of the maternal daily dose passes into milk with no evidence of harm to growth and development; can be prescribed during breastfeeding with monitoring of the infant.International label, same product · College ter Beoordeling van Geneesmiddelen (CBG-MEB) - Geneesmiddeleninformatiebank

• Lynestrenol: Prodrug converted to norethisterone, which binds progesterone receptors; contraception mainly through thickening of cervical mucus, with endometrial and tubal effects and ovulation suppression in about 70% of women (Dutch Exluton SmPC).