سعر سيرتيكان 0.5 مجم 60 قرص 2026

Certican 0.5mg 60 tab.: Egyptian product by Novartis.

• Prophylaxis of organ rejection in adult kidney transplant (low-moderate immunologic risk; with basiliximab, reduced-dose cyclosporine, corticosteroids) and adult liver transplant (start ≥30 days post-transplant; with reduced-dose tacrolimus and corticosteroids) — US Zortress label.Population: Adult transplant recipientsDailyMed (US FDA SPL) — Zortress

• Contraindicated in known hypersensitivity to everolimus, sirolimus, or product components.International label, same formulation · DailyMed (US FDA SPL) — Zortress

• Boxed warnings: malignancies and serious infections from immunosuppression; kidney graft thrombosis; nephrotoxicity; increased mortality in heart transplantation. Only experienced transplant physicians should use. Embryo-fetal toxicity — effective contraception during treatment and 8 weeks after.International label, same formulation · DailyMed (US FDA SPL) — Zortress

• Strong CYP3A4 / P-gp inhibitors or inducersEverolimus is a CYP3A4 and P-gp substrate; avoid or adjust with strong inhibitors/inducers and monitor levels (class labeling).DailyMed (US FDA SPL) — Zortress

• Based on animal data and mechanism, may cause fetal harm. Advise females of reproductive potential of risk and to use effective contraception during treatment and for 8 weeks after final dose.International label, same formulation · DailyMed (US FDA SPL) — Zortress

• Everolimus: Inhibits mammalian target of rapamycin (mTOR), suppressing interleukin-driven T-cell proliferation.