سعر انابراميون 75 مجم 10 اقراص 2022

Ciclosporin (cyclosporine) 75 mg oral tablets listed by Egyptian directories as Anabrammune (Sigma) with the note "n/a yet" (not yet available); 10 tablets per pack. A calcineurin-inhibitor immunosuppressant.

• Prophylaxis of organ rejection in kidney, liver and heart allogeneic transplants (US Neoral indication).Population: Adults and childrenDailyMed (U.S. National Library of Medicine)
• Severe active rheumatoid arthritis not adequately responsive to methotrexate (US Neoral indication).Population: AdultsDailyMed (U.S. National Library of Medicine)
• Severe, recalcitrant plaque psoriasis in non-immunocompromised adults who failed or cannot use other systemic therapy (US Neoral indication).Population: AdultsDailyMed (U.S. National Library of Medicine)

• Hypersensitivity to cyclosporine or any ingredient; in rheumatoid arthritis and psoriasis patients: abnormal renal function, uncontrolled hypertension or malignancy (psoriasis: also no concomitant PUVA/UVB, methotrexate or other immunosuppressants, coal tar or radiation).General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Boxed warning: should be prescribed only by physicians experienced in systemic immunosuppressive therapy; increased susceptibility to infection and possible development of neoplasia (e.g. lymphoma).General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Boxed warning: cyclosporine can cause systemic hypertension and nephrotoxicity; risk increases with dose and duration. Different cyclosporine oral formulations (e.g. Neoral vs Sandimmune) are not bioequivalent and must not be interchanged without physician supervision and blood-level monitoring.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Nephrotoxicity and hepatotoxicity: monitor serum creatinine frequently; take care with other nephrotoxic drugs; monitor elderly patients particularly closely.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Available data have not shown a consistent increase in major birth defects, but cyclosporine exposure in pregnancy (mainly transplant patients) has been associated with increased hypertension, pre-eclampsia, preterm birth and low birth weight.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Cyclosporine is present in human milk; weigh the benefits of breastfeeding against potential adverse effects in the infant.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Ciclosporin (cyclosporine): Specific, reversible inhibition of immunocompetent lymphocytes in the G0/G1 phase, preferentially T-helper cells; also inhibits lymphokine production and release, including interleukin-2 (US Neoral label).