سعر شامبكس 1مجم 28 قرص 2022

Champix 1 mg 28 f.c.tablet: Varenicline (Pfizer).

• Aid to smoking cessation treatment in adults (US varenicline film-coated tablet labeling).DailyMed (U.S. National Library of Medicine)

• Most common AE (>5% and twice placebo): nausea, abnormal dreams, constipation, flatulence, vomiting (US labeling).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• History of serious hypersensitivity or skin reactions to varenicline (US labeling).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Neuropsychiatric adverse events including suicidality; seizures; alcohol interaction; accidental injury; cardiovascular events in patients with underlying CV disease; somnambulism; angioedema; serious skin reactions; nausea (dose-related) (US labeling).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• NRT (nicotine patch)Safety/efficacy of combination not established; higher discontinuation due to AEs (US label).DailyMed (U.S. National Library of Medicine)
• AlcoholIncreased intoxicating effects and unusual behavior reported; reduce alcohol until effect known (US label).DailyMed (U.S. National Library of Medicine)
• Theophylline, warfarin, insulinSmoking cessation may alter PK/PD; dose adjustment may be needed (US label).DailyMed (U.S. National Library of Medicine)

• Available data have not suggested increased major birth-defect risk vs women who smoke; animal developmental toxicity at high exposures; smoking itself harms pregnancy — discuss risks/benefits (US PLLR).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• No human milk data; present in rat milk; monitor infant for seizures and excessive vomiting (US labeling).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Varenicline: Partial agonist at α4β2 nicotinic acetylcholine receptors; reduces craving/withdrawal while blocking nicotine reinforcement (US varenicline labeling / DrugBank).