سعر كلوكسيد 30 كبسولة 2022

Cloxide 30 caps.: Chlordiazepoxide + clidinium bromide (Eva Pharma).

• Combination of chlordiazepoxide (anxiolytic benzodiazepine) and clidinium bromide (anticholinergic antispasmodic) for adjunctive therapy of peptic ulcer and irritable bowel / spastic colon syndromes (US chlordiazepoxide/clidinium class labeling — Librax-type).Population: AdultsDailyMed (U.S. National Library of Medicine)

• Hypersensitivity; glaucoma; prostatic hypertrophy with urinary retention; GI obstruction; severe hepatic disease; concomitant opioids with benzodiazepines — boxed warning risk of profound sedation/respiratory depression/death.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• CNS depression, dependence/withdrawal with benzodiazepine; anticholinergic effects (dry mouth, constipation, blurred vision); elderly sensitivity; avoid alcohol.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Opioids / alcohol / other CNS depressantsProfound sedation, respiratory depressionDailyMed (U.S. National Library of Medicine)
• CYP3A inhibitorsMay increase benzodiazepine levelsDailyMed (U.S. National Library of Medicine)
• Other anticholinergicsAdditive anticholinergic effectsDailyMed (U.S. National Library of Medicine)

• Benzodiazepines may cause fetal harm / neonatal floppy infant; avoid in pregnancy. Anticholinergics — use only if needed.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Chlordiazepoxide: Enhances GABA-A receptor activity producing anxiolytic, sedative and muscle-relaxant effects.
• Clidinium bromide: Antimuscarinic agent that reduces GI motility and secretions.