سعر دارابريم 25 مجم 30 قرص 2022

Daraprim 25mg 30 tab.: Pyrimethamine (Glaxo smithkline).

• Antiprotozoal: toxoplasmosis (with a sulfonamide) and susceptible malaria when used as labeled (US pyrimethamine labeling).Population: Adults and pediatric patients as labeledDailyMed (U.S. National Library of Medicine)

• Anorexia, vomiting, ataxia, tremors, seizures at high dose; hypersensitivity; megaloblastic anemia / pancytopenia with prolonged use (US pyrimethamine).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to pyrimethamine; documented megaloblastic anemia due to folate deficiency (US pyrimethamine label).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Bone marrow suppression; use with folinic acid in prolonged/high-dose regimens; caution in G6PD deficiency with sulfonamide combinations; monitor blood counts (US label).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Pyrimethamine may cause fetal harm; use in pregnancy only if benefit justifies risk; folate supplementation considerations apply (US pyrimethamine labeling).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Pyrimethamine: Inhibits parasitic dihydrofolate reductase, blocking tetrahydrofolate synthesis needed for DNA synthesis.