سعر ابريكس 4000 وحدة دولية/0.4مل 6 سرنجات معبأة 2023

Eprex (epoetin alfa) 4000 IU/0.4 mL solution for injection, box of 6 pre-filled syringes, supplied in Egypt by Janssen Cilag / Soficopharm.

• Treatment of symptomatic anaemia associated with chronic renal failure (CRF) in patients on haemodialysis or peritoneal dialysis.Population: Adults and paediatric patients aged 1 to 18 years on haemodialysis; adults on peritoneal dialysiselectronic medicines compendium (emc), UK
• Treatment of severe anaemia of renal origin accompanied by clinical symptoms in adults with renal insufficiency not yet undergoing dialysis.Population: Adultselectronic medicines compendium (emc), UK
• Treatment of anaemia and reduction of transfusion requirements in adults receiving chemotherapy for solid tumours, malignant lymphoma or multiple myeloma, and at risk of transfusion.Population: Adultselectronic medicines compendium (emc), UK

• The most frequent adverse reaction is a dose-dependent increase in blood pressure or aggravation of existing hypertension. Other common reactions include diarrhoea, nausea, vomiting, pyrexia and headache; influenza-like illness may occur, especially at the start of treatment.International label, same product · electronic medicines compendium (emc), UK

• Hypersensitivity to the active substance or any excipient.International label, same product · electronic medicines compendium (emc), UK
• Patients who develop pure red cell aplasia (PRCA) following treatment with any erythropoietin must not receive Eprex or any other erythropoietin.International label, same product · electronic medicines compendium (emc), UK
• Uncontrolled hypertension.International label, same product · electronic medicines compendium (emc), UK

• Blood pressure may rise during treatment; monitor and control it closely. Hypertensive crisis with encephalopathy and seizures has occurred.International label, same product · electronic medicines compendium (emc), UK
• Use with caution in patients with epilepsy, a history of seizures or conditions predisposing to seizures.International label, same product · electronic medicines compendium (emc), UK
• An increased incidence of thrombotic vascular events has been observed with ESAs; weigh benefits against risks, especially in patients with risk factors.International label, same product · electronic medicines compendium (emc), UK

• CiclosporinCiclosporin is bound by red blood cells, so there is potential for an interaction; monitor blood ciclosporin levels and adjust the dose as haemoglobin rises.electronic medicines compendium (emc), UK

• No adequate and well-controlled studies in pregnant women; animal studies showed reproductive toxicity. Use in pregnancy only if the potential benefit outweighs the potential risk to the fetus; use in pregnant surgical patients in an autologous predonation programme is not recommended.International label, same product · electronic medicines compendium (emc), UK
• It is unknown whether exogenous epoetin alfa is excreted in human milk; use with caution in breastfeeding women, weighing the benefit of breastfeeding to the child against the benefit of therapy to the woman.International label, same product · electronic medicines compendium (emc), UK

• Epoetin alfa: Glycoprotein that stimulates erythropoiesis by the same mechanism as endogenous erythropoietin, acting on erythroid precursors (UK Eprex SmPC section 5.1).