سعر ايتوسيد 50 مجم 4 كبسولات 2022

Etoposide 50 mg soft gelatin capsules, pack of 4 (Etosid; Cipla, India; distributed by Star International Company).

• Small cell lung cancer, first-line treatment in combination with other approved chemotherapeutic agents.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Dose-limiting myelosuppression (granulocyte nadir day 7-14, platelet nadir day 9-16); nausea and vomiting; alopecia; anorexia.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to etoposide or any component of the formulation.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: administer under the supervision of a physician experienced in cancer chemotherapy; severe myelosuppression with resulting infection or bleeding may occur. Myelosuppression resulting in death has been reported.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Cyclosporine (high dose)High-dose cyclosporine (concentrations above 2000 ng/mL) given with oral etoposide increased etoposide exposure (AUC) by about 80% and decreased its clearance; consider dose adjustment.DailyMed (U.S. National Library of Medicine)

• VePesid can cause fetal harm when administered to a pregnant woman (teratogenic in mice and rats); women of childbearing potential should avoid becoming pregnant.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Unknown whether excreted in human milk; because of potential serious adverse reactions in nursing infants, decide whether to discontinue nursing or the drug.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Etoposide: Semisynthetic podophyllotoxin derivative; inhibits topoisomerase II causing DNA strand breaks and arrest in late S/G2 phase (US etoposide labeling).