سعر اكسابين 40 مجم 2024

Enoxaparin sodium 40 mg (4000 IU anti-Xa)/0.4 mL solution for injection in pre-filled syringes; pack of 2 syringes (Wadi El Neel Benta).

• Prophylaxis of venous thromboembolism in surgical patients (moderate/high risk)Population: Adultselectronic medicines compendium (emc)
• Prophylaxis of venous thromboembolism in acutely ill medical patients with reduced mobilityPopulation: Adultselectronic medicines compendium (emc)
• Treatment of deep vein thrombosis and pulmonary embolismPopulation: Adultselectronic medicines compendium (emc)

• Most common: haemorrhage, thrombocytopenia, thrombocytosis; also haemorrhagic anaemia, allergic reactions, injection-site reactions, increased liver enzymes.International label, same formulation · electronic medicines compendium (emc)

• Hypersensitivity to enoxaparin, heparin or other LMWHs; history of immune-mediated HIT within 100 days or circulating antibodies; active clinically significant bleeding or high bleeding-risk conditions; spinal/epidural anaesthesia within 24 h when used for treatment.International label, same formulation · electronic medicines compendium (emc)

• Not interchangeable unit-for-unit with other LMWHs; risk of heparin-induced thrombocytopenia (monitor platelets); haemorrhage risk; spinal/epidural haematoma with neuraxial anaesthesia; mechanical prosthetic heart valves; hyperkalaemia.International label, same formulation · electronic medicines compendium (emc)

• Drugs affecting haemostasis (antiplatelets, NSAIDs, other anticoagulants, thrombolytics)MajorIncreased bleeding risk; discontinue before enoxaparin unless strictly indicated, with close monitoring.electronic medicines compendium (emc)
• Drugs increasing potassium (potassium salts, potassium-sparing diuretics, ACE inhibitors, ARBs)ModerateIncreased risk of hyperkalaemia; monitor potassium.electronic medicines compendium (emc)

• No evidence of placental transfer in 2nd/3rd trimester; no first-trimester information; animal studies negative. Use in pregnancy only if clearly needed, with monitoring for bleeding.International label, same formulation · electronic medicines compendium (emc)
• Can be used during breast-feeding (oral absorption by the infant unlikely).International label, same formulation · electronic medicines compendium (emc)

• Enoxaparin sodium: Binds antithrombin III and potentiates inhibition mainly of factor Xa (high anti-Xa to anti-IIa ratio).