سعر فوكسيم 1 جرام فيال 2024

Cefotaxime 1 g powder for injection (IM/IV), one vial, by Tabuk Pharmaceutical Manufacturing Company; a parenteral third-generation cephalosporin antibiotic.

• Lower respiratory tract infections including pneumonia caused by susceptible organismsPopulation: Adults and childrenDailyMed (U.S. National Library of Medicine)
• Genitourinary infections, including uncomplicated gonorrhoeaPopulation: Adults and childrenDailyMed (U.S. National Library of Medicine)
• Gynaecological infections including pelvic inflammatory disease (add anti-chlamydial cover if C. trachomatis suspected)Population: AdultsDailyMed (U.S. National Library of Medicine)

• Most frequent (>1%): local injection-site reactions (4.3%; phlebitis IV, pain/induration IM), hypersensitivity (2.4%; rash, pruritus, fever, eosinophilia) and gastrointestinal effects (1.4%; colitis, diarrhoea, nausea, vomiting). Less frequent: neutropenia, leukopenia, positive Coombs test, candidiasis, headache, transient liver enzyme and BUN rises; rare severe skin reactions (SJS/TEN).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to cefotaxime sodium or to cephalosporin antibiotics.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Ask about previous hypersensitivity to cefotaxime, cephalosporins, penicillins or other drugs; give with caution to patients with type I hypersensitivity to penicillin; serious reactions may require epinephrine.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Potentially life-threatening arrhythmia has been reported after rapid (<60 s) bolus injection through a central venous catheter; administer only as directed.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Clostridioides difficile-associated diarrhoea can occur, even more than two months after treatment.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Nephrotoxic drugs (aminoglycosides, NSAIDs, furosemide)Cefotaxime may potentiate their nephrotoxic effects.DailyMed (U.S. National Library of Medicine)
• ProbenecidReduces cefotaxime clearance by about 50%; avoid cefotaxime doses above 6 g/day with probenecid.DailyMed (U.S. National Library of Medicine)

• No embryotoxicity or teratogenicity in mice and rats; cefotaxime crosses the placenta; no well-controlled studies in pregnant women; use in pregnancy only if clearly needed.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Excreted in human milk in low concentrations; use with caution in nursing women.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Cefotaxime: Bactericidal; inhibits bacterial cell-wall synthesis via penicillin-binding proteins.