سعر انترون ايه 25 مليون وحدة دولية / 2.5 مل محلول متعدد الجرعات 2022

Intron A: recombinant interferon alfa-2b 25 million IU in 2.5 ml (10 million IU/ml) solution for injection, multidose vial (Schering-Plough/MSD, distributed in Egypt by Egypharma).

• Chronic hepatitis B with evidence of viral replicationPopulation: AdultsEuropean Medicines Agency (EMA)
• Chronic hepatitis C (adults, best combined with ribavirin; children ≥3 years and adolescents with ribavirin)Population: Adults; children ≥3 yearsEuropean Medicines Agency (EMA)
• Hairy cell leukaemiaPopulation: AdultsEuropean Medicines Agency (EMA)

• Most common: pyrexia, fatigue, headache and myalgia (fever and fatigue usually reversible within 72 hours of interruption).International label, same formulation · European Medicines Agency (EMA)

• Hypersensitivity to interferon alfa-2b or excipients; severe pre-existing cardiac disease; severe renal or hepatic dysfunction; epilepsy or compromised CNS function.International label, same formulation · European Medicines Agency (EMA)
• Chronic hepatitis with decompensated cirrhosis; autoimmune hepatitis or history of autoimmune disease; immunosuppressed transplant recipients; uncontrolled thyroid disease; combination with telbivudine.International label, same formulation · European Medicines Agency (EMA)
• Children and adolescents with existing or history of severe psychiatric condition, particularly severe depression, suicidal ideation or attempt.International label, same formulation · European Medicines Agency (EMA)

• Severe psychiatric/CNS effects (depression, suicidal ideation and attempts, aggression, mania) may occur during and after treatment; monitor closely and discontinue if symptoms persist or worsen.International label, same formulation · European Medicines Agency (EMA)
• Fatigue, somnolence or confusion may occur; avoid driving or operating machinery.International label, same formulation · European Medicines Agency (EMA)

• Theophylline / aminophyllineInterferon alfa-2b may reduce theophylline clearance; monitor serum theophylline and adjust dose.European Medicines Agency (EMA)
• TelbivudineCombination is contraindicated.European Medicines Agency (EMA)

• No adequate data in pregnant women; animal studies showed reproductive toxicity; use in pregnancy only if benefit justifies the risk to the foetus. Ribavirin combination is contraindicated in pregnancy.International label, same formulation · European Medicines Agency (EMA)
• Unknown whether excreted in human milk; nursing should be discontinued before starting treatment.International label, same formulation · European Medicines Agency (EMA)

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