سعر ايبانتين 100مجم 50 كبسولة 2024

Ipanten 100 mg (Arab Caps > Acdima International Trading): phenytoin 100 mg oral capsules, pack of 50; a hydantoin antiepileptic.

• Haematopoietic complications, some fatal, have occasionally been reported, including thrombocytopenia, leukopenia, granulocytopenia, agranulocytosis and pancytopenia.General active-ingredient information · electronic medicines compendium (emc), MHRA-authorised SmPC

• Hypersensitivity to phenytoin, other hydantoins or any excipient; co-administration with delavirdine (risk of loss of virological response and resistance).General active-ingredient information · electronic medicines compendium (emc), MHRA-authorised SmPC

• Not effective for absence (petit mal) seizures or seizures due to hypoglycaemia or other metabolic causes; abrupt withdrawal may precipitate status epilepticus, so reduce or substitute gradually (except in allergic or hypersensitivity reactions).General active-ingredient information · electronic medicines compendium (emc), MHRA-authorised SmPC
• Serious cutaneous reactions including Stevens-Johnson syndrome, toxic epidermal necrolysis and DRESS, which can be fatal; HLA-B*1502 may be a risk factor for SJS/TEN in patients of Asian ancestry.General active-ingredient information · electronic medicines compendium (emc), MHRA-authorised SmPC
• Suicidal ideation and behaviour have been reported with antiepileptic agents; a meta-analysis showed a small increased risk.General active-ingredient information · electronic medicines compendium (emc), MHRA-authorised SmPC
• Phenytoin sodium (capsules) and phenytoin base (suspension, chewable tablets) are not necessarily biologically equivalent although 100 mg phenytoin sodium equals 92 mg phenytoin on a molecular-weight basis; take care and monitor serum levels when changing dosage forms.General active-ingredient information · electronic medicines compendium (emc), MHRA-authorised SmPC

• DelavirdineCo-administration is contraindicated: possible loss of virological response and resistance to delavirdine or the NNRTI class.electronic medicines compendium (emc), MHRA-authorised SmPC

• Phenytoin crosses the placenta; prenatal exposure is associated with about 6% major malformations (vs 2-3% in the general population), including orofacial clefts, cardiac and craniofacial defects, nail and digit hypoplasia and growth abnormalities (fetal hydantoin syndrome), and neurodevelopmental disorders have been reported.General active-ingredient information · electronic medicines compendium (emc), MHRA-authorised SmPC
• Women of childbearing potential should receive advice on risks; treatment should be reviewed when pregnancy is planned; avoid sudden discontinuation in pregnancy, and monotherapy is preferred where possible.General active-ingredient information · electronic medicines compendium (emc), MHRA-authorised SmPC
• Phenytoin appears in human milk in low concentrations; breastfeeding is not recommended during treatment.General active-ingredient information · electronic medicines compendium (emc), MHRA-authorised SmPC

• Serum phenytoin level determinations may be needed for optimal dose adjustment; the clinically effective level is usually 10-20 mcg/ml (40-80 micromol/l).General active-ingredient information · electronic medicines compendium (emc), MHRA-authorised SmPC

• Phenytoin: Stabilises neuronal membranes and limits the spread of seizure activity, mainly by blocking voltage-dependent sodium channels.