سعر ليدوكايين هيدروكلوريد 1% مع ابينفرين 0.01مجم/مل 5 امبولات 10 مل 2022

Lidocaine hydrochloride 1% & epinephrine 0.01 mg/ml 5 amp. 10 ml by Pharco b (Egypt): lidocaine hydrochloride with epinephrine solution for injection, an amide local anaesthetic.

• Production of local or regional anaesthesia by infiltration techniques (e.g. percutaneous injection, intravenous regional anaesthesia), peripheral nerve block techniques (e.g. brachial plexus, intercostal) and central neural techniques (lumbar and caudal epidural blocks).Population: Adults and children (doses reduced in children)DailyMed (U.S. National Library of Medicine)

• Central nervous system effects (excitatory and/or depressant): light-headedness, nervousness, apprehension, euphoria, confusion, dizziness, drowsiness, tinnitus, blurred or double vision, vomiting, sensations of heat, cold or numbness, twitching, tremors, convulsions, unconsciousness, respiratory depression and arrest; drowsiness is usually an early sign of a high blood level.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Known history of hypersensitivity to amide-type local anaesthetics.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Should be used only by clinicians experienced in diagnosing and managing dose-related toxicity and other acute emergencies, with oxygen, resuscitative drugs, cardiopulmonary equipment and trained personnel immediately available; delayed management of toxicity or underventilation may lead to acidosis, cardiac arrest and possibly death.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Methaemoglobinaemia has been reported with local anaesthetics; patients with G6PD deficiency, congenital or idiopathic methaemoglobinaemia, cardiac or pulmonary compromise, infants under 6 months and those exposed to oxidising agents are more susceptible. Signs (cyanosis, abnormal blood colour) may be immediate or delayed; discontinue and treat promptly (oxygen, hydration; methylene blue, exchange transfusion or hyperbaric oxygen if severe).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Intra-articular infusion of local anaesthetics after arthroscopic and other surgical procedures is an unapproved use; post-marketing reports of chondrolysis exist.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Drugs associated with methaemoglobinaemia (e.g. nitrates/nitrites, other local anaesthetics, dapsone, sulfonamides, nitrofurantoin, chloroquine, primaquine, phenytoin, sodium valproate, metoclopramide, acetaminophen, quinine)Concurrent exposure increases the risk of methaemoglobinaemia.DailyMed (U.S. National Library of Medicine)
• Creatine phosphokinase (laboratory test)Intramuscular lidocaine may increase creatine phosphokinase levels, which can compromise this test (without isoenzyme separation) for diagnosing acute myocardial infarction.DailyMed (U.S. National Library of Medicine)
• Monoamine oxidase inhibitors or tricyclic antidepressantsLocal anaesthetic solutions containing epinephrine may produce severe, prolonged hypertension in patients receiving these drugs; concurrent use should generally be avoided or carefully monitored.DailyMed (U.S. National Library of Medicine)

• Historical US Pregnancy Category B: reproduction studies in rats at up to 6.6 times the human dose showed no fetal harm, but there are no adequate and well-controlled studies in pregnant women; consider this before use in women of childbearing potential, especially in early pregnancy (organogenesis).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• It is not known whether lidocaine is excreted in human milk (per this label); caution should be exercised when it is given to a nursing woman.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Lidocaine: Stabilises the neuronal membrane by inhibiting the ionic (sodium) fluxes required for initiation and conduction of nerve impulses, producing local anaesthesia.
• Epinephrine (adrenaline): Alpha- and beta-adrenergic agonist; in local anaesthetic solutions it causes local vasoconstriction, slowing absorption and prolonging anaesthesia.