سعر ليدوفلاك 8 مجم 10 كبسولات 2022

Lidoflak 8 mg 10 capsules by Mash premiere (Egypt): silodosin 8 mg capsules, a selective alpha-1A blocker for urinary symptoms of benign prostatic hyperplasia.

• Treatment of the signs and symptoms of benign prostatic hyperplasia (BPH); not indicated for hypertension.Population: Adult menDailyMed (U.S. National Library of Medicine)

• Most common (> 2%): retrograde ejaculation, dizziness, diarrhoea, orthostatic hypotension, headache, nasopharyngitis and nasal congestion; retrograde ejaculation (2.8%) was the most common reason for discontinuation and is reversible on stopping.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Severe renal impairment (CrCl < 30 mL/min).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Severe hepatic impairment (Child-Pugh score >= 10).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Concomitant strong CYP3A4 inhibitors (e.g. ketoconazole, clarithromycin, itraconazole, ritonavir).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Postural hypotension, with or without symptoms (e.g. dizziness), and possible syncope when starting treatment; caution about driving, operating machinery or hazardous tasks.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Moderate renal impairment roughly triples silodosin exposure; reduce the dose to 4 mg and monitor for adverse events.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Do not combine with other alpha-blockers; use caution with antihypertensives and PDE5 inhibitors (possible symptomatic hypotension).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Strong CYP3A4 inhibitors (ketoconazole, itraconazole, clarithromycin, ritonavir)Ketoconazole 400 mg increased silodosin Cmax 3.8-fold and AUC 3.2-fold; concomitant use is contraindicated.DailyMed (U.S. National Library of Medicine)
• Moderate CYP3A4 inhibitors (e.g. diltiazem, erythromycin, verapamil)May increase silodosin concentrations (not evaluated); use caution and monitor for adverse events.DailyMed (U.S. National Library of Medicine)
• Other alpha-blockersInteractions expected; silodosin should not be combined with other alpha-blockers.DailyMed (U.S. National Library of Medicine)

• Silodosin is not indicated for use in females.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Silodosin is not indicated for use in females.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Silodosin: Selective antagonist of post-synaptic alpha-1A adrenoreceptors in the prostate, bladder base, bladder neck and prostatic urethra; smooth-muscle relaxation improves urine flow and BPH symptoms.