سعر ماجيتامسولوسين 0.4مجم 30 كبسولة ممتدة المفعول 2023

Magitamsulosin 0.4 mg extended-release capsules (Medizen / Magic Pharma), pack of 30: tamsulosin, an alpha-1 adrenergic blocker for the signs and symptoms of benign prostatic hyperplasia.

• Treatment of the signs and symptoms of benign prostatic hyperplasia (BPH). Not indicated for the treatment of hypertension.Population: Adult menDailyMed (U.S. National Library of Medicine)

• Most common (2% or more and more than placebo, 0.4 or 0.8 mg): headache, dizziness, rhinitis, infection, abnormal ejaculation (8.4% at 0.4 mg, 18.1% at 0.8 mg), asthenia, back pain, diarrhoea, pharyngitis, chest pain, increased cough, somnolence, nausea, sinusitis, insomnia, decreased libido, tooth disorder and blurred vision.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to tamsulosin hydrochloride or any component (reactions have included rash, urticaria, pruritus, angioedema and respiratory symptoms).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Orthostasis (postural hypotension, dizziness, vertigo) and potential syncope; avoid situations where injury could result.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Intraoperative floppy iris syndrome during cataract or glaucoma surgery in patients on or previously treated with alpha-1 blockers; inform the ophthalmologist. Initiating tamsulosin in patients scheduled for cataract or glaucoma surgery is not recommended.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Priapism (rare, probably less than 1 in 50,000) can lead to permanent impotence if untreated. Screen for prostate cancer before starting (BPH and cancer may coexist). Caution with serious sulfa allergy.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Strong CYP3A4 inhibitors (e.g. ketoconazole)Ketoconazole increased tamsulosin Cmax and AUC 2.2- and 2.8-fold; do not use 0.4 mg tamsulosin with strong CYP3A4 inhibitors.DailyMed (U.S. National Library of Medicine)
• Moderate CYP3A4 inhibitors (e.g. erythromycin), CYP2D6 inhibitors (e.g. paroxetine, terbinafine), cimetidineUse with caution, particularly at doses above 0.4 mg (paroxetine increased AUC 1.6-fold).DailyMed (U.S. National Library of Medicine)
• Other alpha-adrenergic blockersShould not be used in combination (expected additive hypotension).DailyMed (U.S. National Library of Medicine)

• Tamsulosin is not indicated for use in women; no adequate human data, and no adverse developmental effects in rat and rabbit studies.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Not indicated for use in women; no data on presence in human milk (present in rat milk).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Tamsulosin: Selective antagonist of alpha-1 adrenoceptors (predominantly alpha-1A) in the prostate, prostatic capsule, prostatic urethra and bladder neck; blocking them relaxes smooth muscle and improves urine flow and BPH symptoms.