سعر ليفاجول 450مجم 20 كبسولة 2024

Livagoal 450 mg (Marcyrl, Egypt): ursodeoxycholic acid 450 mg capsules, pack of 20; a hydrophilic bile acid used for cholesterol gallstones and chronic cholestatic liver disease.

• In US gallstone-dissolution trials, adverse events occurred at similar rates with ursodiol and placebo; commonly reported events included abdominal pain, diarrhoea, nausea, dyspepsia, constipation, vomiting, headache and viral infection.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Not effective for calcified cholesterol stones, radiopaque stones or radiolucent bile pigment stones; patients with such stones are not candidates.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Patients with compelling reasons for cholecystectomy (unremitting acute cholecystitis, cholangitis, biliary obstruction, gallstone pancreatitis or biliary-gastrointestinal fistula) are not candidates.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Allergy to bile acids.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Rare post-marketing reports of enteroliths (bezoars) causing obstruction requiring surgery in patients predisposed to intestinal stenosis or stasis (e.g. surgical enteroanastomoses, Crohn's disease); withhold treatment and evaluate if obstructive symptoms occur.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Bile acid sequestrants (cholestyramine, colestipol) and aluminium-based antacidsMay reduce ursodiol absorption and interfere with its action.DailyMed (U.S. National Library of Medicine)
• Oestrogens, oral contraceptives, clofibrate (and perhaps other lipid-lowering drugs)Increase hepatic cholesterol secretion and encourage cholesterol gallstone formation, so may counteract ursodiol.DailyMed (U.S. National Library of Medicine)

• No adequate and well-controlled studies in pregnant women; animal studies at 20- to 100-fold human doses showed no fetal harm, but fetal harm cannot be ruled out and the US label does not recommend use during pregnancy.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Ursodeoxycholic acid: Hydrophilic bile acid that decreases the cholesterol saturation of bile.