سعر جالديبيدرا 300 مجم اقراص 2022

Galldepedra 300 mg film-coated tablets (EGPI for Jasper Pharmaceutical Industries, Egypt): ursodeoxycholic acid 300 mg per tablet, a hydrophilic bile acid. Pack size was not stated by the sources opened.

• Most common (1% or more): abdominal discomfort, abdominal pain, alopecia, diarrhoea, nausea, pruritus and rash.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Complete biliary obstruction; known hypersensitivity or intolerance to ursodiol or any component.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Monitor liver function tests and bilirubin (monthly for 3 months, then every 6 months in PBC); consider stopping if they rise significantly. Watch for obstructive symptoms (enteroliths) in patients at risk of intestinal stenosis or stasis.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Bile acid sequestrants (cholestyramine, colestipol)May reduce ursodiol absorption.DailyMed (U.S. National Library of Medicine)
• Aluminium-based antacidsAdsorb bile acids and may reduce ursodiol absorption.DailyMed (U.S. National Library of Medicine)
• Estrogens, oral contraceptives, clofibrate and other lipid-altering drugsIncrease hepatic cholesterol secretion and may counteract ursodiol.DailyMed (U.S. National Library of Medicine)

• Published data over decades have not identified a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes; most exposures were in the second and third trimesters.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Liver function tests (GGT, alkaline phosphatase, AST, ALT) and bilirubin during treatment.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Ursodeoxycholic acid: Hydrophilic bile acid that decreases cholesterol saturation of bile and may protect hepatocytes.