سعر لونجاسيف 1 جم فيال وريد 2024

Ceftriaxone 1 g powder for intravenous injection, single vial (The United Pharmaceuticals Co Ltd-Jordan > Modern Pharma).

• Lower respiratory tract, skin and skin structure, urinary tract, bone and joint and intra-abdominal infections, bacterial septicemia, meningitis, acute bacterial otitis media, uncomplicated gonorrhea and pelvic inflammatory disease caused by susceptible organisms; surgical prophylaxis.Population: Adults and pediatric patients (neonatal restrictions apply)DailyMed (U.S. National Library of Medicine)

• Reported adverse reactions include local reactions (pain, induration, phlebitis), rash, eosinophilia (6%), thrombocytosis (5.1%), leukopenia, diarrhea/loose stools (2.7%) and elevated liver enzymes.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to ceftriaxone, any excipient or any other cephalosporin.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Premature neonates up to a postmenstrual age of 41 weeks; hyperbilirubinemic neonates (risk of bilirubin encephalopathy).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Neonates (28 days or younger) requiring or expected to require calcium-containing IV solutions, including continuous calcium-containing infusions such as parenteral nutrition (fatal ceftriaxone-calcium precipitates reported).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Serious hypersensitivity reactions including anaphylaxis may occur; patients with previous hypersensitivity to penicillins or other beta-lactams may be at greater risk.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Do not mix with or administer simultaneously with calcium-containing IV solutions (precipitation); in patients other than neonates sequential administration is possible if lines are thoroughly flushed.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Serious neurological adverse reactions (encephalopathy, seizures, myoclonus, non-convulsive status epilepticus) have been reported; discontinue if they occur.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Calcium-containing IV solutions (e.g., Ringer's, Hartmann's, parenteral nutrition)Precipitation of ceftriaxone-calcium; contraindicated in neonates; in others administer sequentially with thorough line flushing.DailyMed (U.S. National Library of Medicine)
• Vitamin K antagonists (e.g., warfarin)May increase bleeding risk; monitor coagulation parameters frequently and adjust anticoagulant dose.DailyMed (U.S. National Library of Medicine)

• Animal studies showed no embryotoxicity, fetotoxicity or teratogenicity, but there are no adequate and well-controlled studies in pregnant women; use during pregnancy only if clearly needed.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Low concentrations of ceftriaxone are excreted in human milk; use caution in nursing women.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Ceftriaxone: Bactericidal; inhibits bacterial cell wall synthesis; active in the presence of some beta-lactamases (US label).