سعر ماكسيبيم 2جم فيال 2023

Cefepime 2 g powder for injection (one vial).

• Moderate to severe pneumonia caused by susceptible organisms.Population: Adults and children 2 months-16 yearsDailyMed (U.S. National Library of Medicine)
• Empiric therapy for febrile neutropenic patients.Population: Adults and children 2 months-16 yearsDailyMed (U.S. National Library of Medicine)
• Uncomplicated and complicated urinary tract infections including pyelonephritis.Population: Adults and children 2 months-16 yearsDailyMed (U.S. National Library of Medicine)

• Most common (>=1%): local infusion-site reactions, positive Coombs test, decreased phosphorus, increased ALT/AST, increased PT/PTT and rash; at 2 g every 8 h also diarrhoea, nausea, vomiting, pruritus, fever and headache.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Immediate hypersensitivity to cefepime, other cephalosporins, penicillins or other beta-lactams.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity reactions; cross-hypersensitivity with penicillins may occur in up to 10% of penicillin-allergic patients.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Neurotoxicity (encephalopathy, aphasia, myoclonus, seizures, nonconvulsive status epilepticus), mostly in renal impairment without dose adjustment; discontinue if it occurs.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Clostridioides difficile-associated diarrhoea; use only for proven or strongly suspected bacterial infections to limit resistance.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• AminoglycosidesMonitor renal function because of potential nephrotoxicity and ototoxicity of aminoglycosides.DailyMed (U.S. National Library of Medicine)
• Potent diuretics (e.g. furosemide)Nephrotoxicity has been reported with cephalosporins plus potent diuretics; monitor renal function.DailyMed (U.S. National Library of Medicine)

• Decades of observational data with cephalosporins have not established drug-associated risks of major birth defects, miscarriage or adverse outcomes; cefepime caused no adverse developmental effects in animal studies.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Cefepime is present in human milk at low concentrations (about 0.5 mcg/mL after a 1 g IV dose); weigh breastfeeding benefits against maternal need and potential infant effects.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Cefepime: Binds penicillin-binding proteins and inhibits bacterial cell-wall synthesis.