سعر اونسيم 500 مجم فيال 2022

Onsime (cefepime) 500 mg powder for IM/IV injection, single vial; fourth-generation cephalosporin.

• Pneumonia (moderate to severe)DailyMed (U.S. NLM)
• Empiric therapy for febrile neutropenic patientsDailyMed (U.S. NLM)
• Uncomplicated and complicated urinary tract infections including pyelonephritisDailyMed (U.S. NLM)

• Most common (>=1%): local reactions, positive Coombs test, decreased phosphorus, increased ALT/AST, increased PT/PTT, rash.International label, equivalent formulation · DailyMed (U.S. NLM)

• Immediate hypersensitivity to cefepime, other cephalosporins, penicillins or other beta-lactams.International label, equivalent formulation · DailyMed (U.S. NLM)

• Hypersensitivity: cross-reactivity with penicillin allergy in up to 10%; discontinue if allergic reaction occurs.International label, equivalent formulation · DailyMed (U.S. NLM)
• Neurotoxicity (encephalopathy, seizures), especially with unadjusted doses in renal impairment; discontinue if it occurs.International label, equivalent formulation · DailyMed (U.S. NLM)
• Clostridioides difficile-associated diarrhoea: evaluate if diarrhoea occurs.International label, equivalent formulation · DailyMed (U.S. NLM)

• Decades of observational data with cephalosporins have not established a drug-associated risk of major birth defects, miscarriage or adverse outcomes.International label, equivalent formulation · DailyMed (U.S. NLM)

• Cefepime: Bactericidal; binds penicillin-binding proteins and inhibits bacterial cell-wall synthesis (DrugBank/US labels).