سعر ميتودوبكس شراب 0.1 جم/100 مل 2022

Metodopex (metopimazine) oral liquid (Global Napi Pharmaceuticals), an antiemetic; listed as syrup in the source sheet and as 100 ml oral drops containing 0.1 g/100 ml by Rosheta.

• Rare: sedation or drowsiness, orthostatic hypotension, dry mouth, constipation, accommodation disorders, urinary retention; very rare: extrapyramidal symptoms (early dyskinesia), hyperprolactinaemia, gynaecomastia, galactorrhoea, amenorrhoea, rash, impotence.General active-ingredient information · Agence nationale de sécurité du médicament et des produits de santé (ANSM), France

• Risk of angle-closure glaucoma; risk of urinary retention linked to urethroprostatic disorders; hypersensitivity to metopimazine or excipients; combination with dopaminergic agonists or levodopa.General active-ingredient information · Agence nationale de sécurité du médicament et des produits de santé (ANSM), France

• The French solution contains sodium metabisulfite (risk of severe allergic reactions and bronchospasm), ethanol, sucrose and parabens; caution in the elderly (sedation, hypotension) and in renal or hepatic impairment (risk of overdose); avoid alcohol. Excipients of the Egyptian product were not available.General active-ingredient information · Agence nationale de sécurité du médicament et des produits de santé (ANSM), France

• Dopaminergic agonists and levodopaContraindicated combination: reciprocal antagonism between the dopaminergic agent and the antiemetic neuroleptic.Agence nationale de sécurité du médicament et des produits de santé (ANSM), France
• Alcohol and other CNS depressants (opioids, benzodiazepines, sedating antihistamines, etc.)Increased sedation and impaired alertness; avoid alcohol.Agence nationale de sécurité du médicament et des produits de santé (ANSM), France
• Antihypertensives, beta-blockers and nitratesAdditive risk of hypotension, especially orthostatic.Agence nationale de sécurité du médicament et des produits de santé (ANSM), France
• Gastrointestinal topical agents, antacids and charcoalReduce absorption; take more than 2 hours apart.Agence nationale de sécurité du médicament et des produits de santé (ANSM), France

• Use with caution during pregnancy in the absence of usable clinical data.General active-ingredient information · Agence nationale de sécurité du médicament et des produits de santé (ANSM), France
• Use with caution during breastfeeding in the absence of usable clinical data.General active-ingredient information · Agence nationale de sécurité du médicament et des produits de santé (ANSM), France

• Metopimazine: Phenothiazine antiemetic with selective antidopaminergic (anti-apomorphine) activity and very limited passage across the blood-brain barrier; rapidly metabolised to metopimazine acid, which is also antiemetic (French SmPC).