سعر ميكروجينست 30/150 ميكروجرام 21 قرص 2024

Microgenest tablets with levonorgestrel 150 mcg and ethinylestradiol 30 mcg, 21 tablets (Acdima), a combined oral contraceptive.

• Oral contraception (and recognised gynaecological indications for oestrogen-progestogen combinations).Population: Women of reproductive ageelectronic medicines compendium (emc), UK

• Most common (>= 1%): nausea, abdominal pain, weight gain, headache, depressed or altered mood, breast pain and tenderness; serious: arterial and venous thromboembolism.International label, same formulation · electronic medicines compendium (emc), UK

• Combined hormonal contraceptives must not be used with current or past venous thromboembolism or a known predisposition (e.g. Factor V Leiden, antithrombin III, protein C or S deficiency), major surgery with prolonged immobilisation, current or past arterial thromboembolism (e.g. myocardial infarction, angina) or cerebrovascular disease, among other conditions listed in the SmPC.International label, same formulation · electronic medicines compendium (emc), UK

• Any combined hormonal contraceptive increases the risk of venous thromboembolism; the woman's individual risk factors should be assessed and she should seek urgent care for symptoms of DVT or pulmonary embolism.International label, same formulation · electronic medicines compendium (emc), UK
• ALT elevations above 5 times the upper limit of normal occurred more often in women using ethinylestradiol-containing products during hepatitis C treatment with ombitasvir/paritaprevir/ritonavir and dasabuvir.International label, same formulation · electronic medicines compendium (emc), UK

• Enzyme inducers incl. St John's wort (Hypericum perforatum), ritonavir, nelfinavir, nevirapineListed in the SmPC among substances that can interact with COCs by altering sex-hormone clearance, which may reduce contraceptive efficacy.electronic medicines compendium (emc), UK

• Not indicated during pregnancy; stop if pregnancy occurs. Epidemiological studies show no increased risk of birth defects with inadvertent use in early pregnancy.International label, same formulation · electronic medicines compendium (emc), UK
• Use during lactation may reduce milk volume and change its composition; minute amounts pass into milk, so another contraceptive method may be advised for breast-feeding mothers.International label, same formulation · electronic medicines compendium (emc), UK

• Levonorgestrel: Delays or inhibits ovulation; may also affect cervical mucus and endometrium.
• Ethinylestradiol: As part of an estrogen-progestogen combination: inhibits ovulation by suppressing the mid-cycle LH surge, thickens cervical mucus and makes the endometrium unreceptive to implantation.