سعر ميوكوبراف فوار 600مجم 10 اكياس 2024

Mucobrave acetylcysteine 600 mg effervescent sachets (Xeedia Pharma); mucolytic, box of 10 sachets.

• Mucolytic therapy in chronic bronchitis and other respiratory conditions associated with thick mucus hypersecretion (adults).Population: AdultsHealth Products Regulatory Authority (HPRA)

• Uncommon: hypersensitivity, headache, tinnitus, tachycardia, hypotension, vomiting, diarrhoea, stomatitis, abdominal pain, nausea, urticaria, rash, angioedema, pruritus, fever. Rare: bronchospasm, dyspnoea, dyspepsia. Very rare: anaphylactic reactions, haemorrhage.International label, equivalent formulation · Health Products Regulatory Authority (HPRA)

• Hypersensitivity to acetylcysteine or to any excipient.International label, equivalent formulation · Health Products Regulatory Authority (HPRA)
• Children under 2 years of age (mucolytics may obstruct their airways).International label, equivalent formulation · Health Products Regulatory Authority (HPRA)

• Serious skin reactions (e.g. Stevens-Johnson syndrome, toxic epidermal necrolysis) have rarely been reported; stop acetylcysteine and seek medical advice at once if new skin or mucosal changes occur.International label, equivalent formulation · Health Products Regulatory Authority (HPRA)
• Use with caution in asthma (risk of bronchospasm; stop immediately if it occurs) and in patients with a history of peptic ulcer.International label, equivalent formulation · Health Products Regulatory Authority (HPRA)
• Especially at the start of treatment, bronchial secretions may become thinner and larger in volume; if the patient cannot expectorate adequately, supportive measures (postural drainage, suction) are needed.International label, equivalent formulation · Health Products Regulatory Authority (HPRA)

• AntitussivesConcomitant antitussives may cause dangerous accumulation of secretions because the cough reflex is reduced.Health Products Regulatory Authority (HPRA)
• Glyceryl trinitrate (nitroglycerin)Acetylcysteine may enhance the vasodilatory and antiplatelet effect of glyceryl trinitrate; monitor for hypotension (possibly with headache) if co-administered.Health Products Regulatory Authority (HPRA)
• Activated charcoalActivated charcoal may reduce the effect of acetylcysteine.Health Products Regulatory Authority (HPRA)

• There are no or limited data in pregnant women and animal studies are insufficient; not recommended during pregnancy.International label, equivalent formulation · Health Products Regulatory Authority (HPRA)
• It is unknown whether acetylcysteine passes into human milk; a risk to the infant cannot be excluded, so decide whether to stop breastfeeding or therapy.International label, equivalent formulation · Health Products Regulatory Authority (HPRA)

• Acetylcysteine: Lowers the viscosity of mucous and mucopurulent secretions by depolymerising mucoprotein complexes (free thiol group), and acts as a direct antioxidant.