سعر نيرهاسيلدا 25مجم 16 فيلم 2023

Sildenafil 25 mg orodispersible film (Nerhadou International Co.); PDE5 inhibitor listed by Egyptian directories as a men's tonic for erectile dysfunction.

• Treatment of erectile dysfunction.Population: Adult menDailyMed (U.S. National Library of Medicine)

• Most common adverse reactions (≥2%): headache, flushing, dyspepsia, abnormal vision, nasal congestion, back pain, myalgia, nausea, dizziness and rash.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Use in patients taking nitric oxide donors such as organic nitrates or nitrites in any form (regularly or intermittently), because sildenafil potentiates their hypotensive effect.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Known hypersensitivity to sildenafil or any tablet component.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Co-administration with guanylate cyclase stimulators such as riociguat.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Cardiovascular: sexual activity carries a potential cardiac risk in patients with pre-existing cardiovascular disease; ED treatments should generally not be used in men for whom sexual activity is inadvisable.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Prolonged erection (>4 hours) and priapism have been reported; seek immediate medical help if an erection lasts longer than 4 hours.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Stop use and seek medical attention for sudden loss of vision in one or both eyes (possible NAION) or sudden decrease or loss of hearing.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Nitrates / nitric oxide donorsContraindicated: sildenafil potentiates the hypotensive effects of nitrates.DailyMed (U.S. National Library of Medicine)
• Alpha-blockersAdditive blood-pressure lowering; patients should be stable on the alpha-blocker and sildenafil started at 25 mg.DailyMed (U.S. National Library of Medicine)
• RitonavirIncreases sildenafil AUC about 11-fold; do not exceed a single 25 mg dose in 48 hours.DailyMed (U.S. National Library of Medicine)

• Not indicated for use in females; no human pregnancy data; animal studies in rats and rabbits showed no adverse developmental outcomes at high doses.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Not indicated for use in females; limited data indicate sildenafil and its active metabolite are present in human milk.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Sildenafil: Inhibits PDE5, the enzyme that degrades cGMP in the corpus cavernosum, enhancing the nitric oxide effect during sexual stimulation (smooth-muscle relaxation and inflow of blood).