سعر اوكتوزنريف 6/25مجم 30 كبسولة 2025

Olanzapine + fluoxetine 6/25 mg capsules (Octozinreef, October Pharma, Egypt); pack of 30 capsules.

• Acute depressive episodes associated with bipolar I disorder (adults and children/adolescents 10-17 years).DailyMed (U.S. NLM)
• Treatment-resistant depression (major depressive disorder not responding to 2 separate trials of different antidepressants of adequate dose and duration in the current episode) in adults.Population: AdultsDailyMed (U.S. NLM)

• Most common (adults): sedation, weight increased, appetite increased, dry mouth, fatigue, oedema, tremor, disturbance in attention, blurred vision.International label, same formulation · DailyMed (U.S. NLM)

• Use of an MAOI intended to treat psychiatric disorders with this product or within 5 weeks of stopping it, or use within 14 days of stopping an MAOI; starting in patients treated with linezolid or intravenous methylene blue.International label, same formulation · DailyMed (U.S. NLM)
• Concomitant use with pimozide or thioridazine.International label, same formulation · DailyMed (U.S. NLM)

• Boxed warning: increased risk of suicidal thoughts and behaviours in children, adolescents and young adults taking antidepressants; monitor closely for clinical worsening and emergence of suicidal thoughts.International label, same formulation · DailyMed (U.S. NLM)
• Boxed warning: elderly patients with dementia-related psychosis treated with antipsychotics are at increased risk of death; not approved for dementia-related psychosis.International label, same formulation · DailyMed (U.S. NLM)
• Other warnings include serotonin syndrome, neuroleptic malignant syndrome, DRESS, and metabolic changes (hyperglycaemia/diabetes, dyslipidaemia, weight gain).International label, same formulation · DailyMed (U.S. NLM)

• Third-trimester exposure to antipsychotics (including olanzapine) risks extrapyramidal and/or withdrawal symptoms in neonates; SSRI exposure late in pregnancy may increase risk of persistent pulmonary hypertension of the newborn and of postpartum haemorrhage; available data have not established a drug-associated risk of major birth defects.International label, same formulation · DailyMed (U.S. NLM)
• Olanzapine, fluoxetine and norfluoxetine are present in human milk; monitor breastfed infants for sedation, agitation, irritability, poor feeding and poor weight gain.International label, same formulation · DailyMed (U.S. NLM)

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