سعر اورنيهيباريت 5 مجم /10مل 5 امبولات 2025

L-ornithine-L-aspartate 5 g/10 ml concentrate for intravenous infusion, 5 ampoules (Orniheparate, Rotabiogen).

• Treatment of latent and manifest hepatic encephalopathy.Population: Adults (core SPC; limited paediatric experience)Merz Pharmaceuticals GmbH

• Uncommon: nausea; rare: vomiting; these gastrointestinal effects are generally transient and disappear on reducing the dose or infusion rate.International label, equivalent formulation · Merz Pharmaceuticals GmbH
• Frequency not known: hypersensitivity and anaphylactic reaction (Merz prescribing information for the infusion concentrate).International label, equivalent formulation

• Hypersensitivity to L-ornithine-L-aspartate.International label, equivalent formulation · Merz Pharmaceuticals GmbH
• Severely impaired renal function (serum creatinine above 3 mg/100 ml).International label, equivalent formulation · Merz Pharmaceuticals GmbH

• At high doses serum and urine urea should be monitored.International label, equivalent formulation · Merz Pharmaceuticals GmbH

• No clinical data in pregnancy and reproductive toxicity has not been studied in animals; avoid in pregnancy unless the benefit clearly outweighs the risk.International label, equivalent formulation · Merz Pharmaceuticals GmbH
• Unknown whether it passes into breast milk; avoid during lactation unless the benefit outweighs the risk.International label, equivalent formulation · Merz Pharmaceuticals GmbH

• L-ornithine-L-aspartate (ornithine aspartate): Ornithine and aspartate act on the two main ammonia detoxification pathways: ornithine activates and is a substrate of hepatic urea synthesis, and both supply glutamate for glutamine synthesis, lowering blood ammonia.