سعر بانادول ادفانس 500مجم 48 قرص 2024

Paracetamol 500 mg film-coated tablets with a fast-disintegrating formulation (Panadol Advance), 48 tablets per pack, marketed in Egypt.

• Mild analgesic and antipyretic for painful and febrile conditions (headache incl. migraine and tension headache, toothache, backache, rheumatic and muscle pain, dysmenorrhoea, sore throat, colds and flu, non-serious arthritis pain)electronic medicines compendium (emc)

• Very rare: thrombocytopenia, agranulocytosis, anaphylaxis, cutaneous hypersensitivity including serious skin reactions, bronchospasm (mainly in aspirin/NSAID-sensitive asthmatics), hepatic dysfunction; not known: high anion gap metabolic acidosis.International label, same formulation · electronic medicines compendium (emc)

• Hypersensitivity to paracetamol or any of the other constituents.International label, same formulation · electronic medicines compendium (emc)

• Do not use with other paracetamol-containing products; underlying liver disease increases the risk of liver damage; patients with liver or kidney impairment should seek medical advice; do not exceed the stated dose.International label, same formulation · electronic medicines compendium (emc)
• High anion gap metabolic acidosis due to pyroglutamic acidosis has been reported in patients with severe illness, malnutrition or glutathione deficiency, especially with prolonged use or with flucloxacillin.International label, same formulation · electronic medicines compendium (emc)

• Warfarin and other coumarinsProlonged regular daily paracetamol may enhance the anticoagulant effect with increased bleeding risk; occasional doses have no significant effect.electronic medicines compendium (emc)
• Metoclopramide, domperidone, colestyramineAbsorption speed may be increased by metoclopramide or domperidone and reduced by colestyramine.electronic medicines compendium (emc)
• FlucloxacillinConcurrent use associated with high anion gap metabolic acidosis due to pyroglutamic acidosis, especially in patients with risk factors.electronic medicines compendium (emc)

• If clinically needed, paracetamol can be used in pregnancy at the lowest effective dose for the shortest possible time; neurodevelopment studies are inconclusive.International label, same formulation · electronic medicines compendium (emc)
• Excreted in breast milk but not in clinically significant amounts at recommended doses; breastfeeding is not contraindicated.International label, same formulation · electronic medicines compendium (emc)

• Paracetamol: Antipyretic analgesic; mechanism probably involves (selective) inhibition of prostaglandin synthesis, mainly centrally.