سعر بيميتريكسيد سينثون 500مجم/20 مل فيال 2024

Pemetrexed 500 mg/20 ml for intravenous infusion, an antifolate chemotherapy agent.

• Non-squamous non-small cell lung cancer (combination first-line, maintenance or second-line, per label)Population: AdultsDailyMed (U.S. National Library of Medicine)

• History of severe hypersensitivity reaction to pemetrexed (US label).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Can cause severe myelosuppression; do not give when ANC is below 1500 cells/mm3 or platelets below 100,000 cells/mm3 (US label).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Can cause severe, sometimes fatal, renal failure (US label).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• IbuprofenIncreases pemetrexed exposure; avoid from 2 days before to 2 days after dosing when creatinine clearance is 45-79 mL/min (US label).DailyMed (U.S. National Library of Medicine)

• Can cause fetal harm; females should use contraception for 6 months and males for 3 months after the last dose (US label).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Do not breastfeed during treatment and for 1 week after the last dose (US label).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Pemetrexed: Inhibits thymidylate synthase, dihydrofolate reductase and glycinamide ribonucleotide formyltransferase.